Results 31 to 40 of about 1,000,149 (236)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The skewness of science in 219 sub-fields and a number of aggregates [PDF]
This paper studies evidence from Thomson Scientific about the citation process of 3.7 million articles published in the period 1998-2002 in 219 Web of Science categories, or sub-fields.
Javier Ruiz-Castillo +3 more
core +2 more sources
Scientific Data: an open access and open data publication to facilitate reproducible research
, 2014 As open access to journal articles has become more established in scholarly publishing, a number of Scientific Technical and Medical (STM) publishers are working to help provide open access to research data (open data).
Scientific Data (663274)
core +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
The citation merit of scientific publications [PDF]
We propose a new method to assess the merit of any set of scientific papers in a given field based on the citations they receive. Given a citation indicator, such as the mean citation or the h-index, we identify the merit of a given set of n articles ...
Javier Ruiz-Castillo +2 more
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Automatic summarization of scientific articles: A survey
, 2022 The scientific research process generally starts with the examination of the state of the art, which may involve a vast number of publications. Automatically summarizing scientific articles would help researchers in their investigation by speeding up the
Nouf Ibrahim Altmami +1 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Citation classics in systematic reviews and meta-analyses : who wrote the top 100 most cited articles? [PDF]
, 2013 Background: Systematic reviews of the literature occupy the highest position in currently proposed hierarchies of evidence. The aims of this study were to assess whether citation classics exist in published systematic review and meta-analysis (SRM ...
Clarke Aileen +14 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source