Results 61 to 70 of about 15,656,567 (266)

Liberate the Article! Proposals for Simplified Scientific Writing Conventions

M@n@gement
A huge amount of advice and guidance has been provided on how to craft articles for top-tier journals. Simultaneously, research publications themselves have been criticized as formulaic or even nonsensical by some scholars.
Hervé Laroche
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Research Focus International Scientific Journal

, 2023
It is intended for scientists, teachers, researchers and specialists of various fields of higher education and research institutions. The editorial staff consists of a team of famous scientists who have achieved high scientific achievements in the fields
Research Focus International Scientific Journal
core   +2 more sources

Pearls for publishing papers: Tips and tricks

Indian Journal of Dermatology, 2016
With the stringent regulations from various academic bodies making it desirable for a post graduate resident to have submitted an original article prior to appearance for their exams or those working in teaching institutions to have published articles to
Karalikkattil T Ashique, Feroze Kaliyadan   +1 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

An Assessment of Scientific Productivity: Review in the Area of Agricultural and Biological Sciences in Ecuador Using Scientometrics and Lotka’s Law

Publications
Scientific production is a key indicator of a country’s academic and institutional development. This review followed a quantitative and descriptive bibliometric design using Lotka’s Law, aimed at analysing Ecuador’s scientific production in the area of ...
William Viera-Arroyo, Lya Vera, Martín Moya, Duther López, Wilson Vásquez-Castillo, Carlos Caicedo   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

MENINGKATKAN KUALITAS PENULISAN KARYA ILMIAH GURU-GURU SEKOLAH MENENGAH ATAS DI PARAKAN TEMANGGUNG

Rekayasa, 2016
Partners of this community service wereMadrasah Aliyah Negeri Parakan and SMK 17 Parakan Temanggung, Temanggung. This community serviceactivity was aimed atovercoming some of the problems faced by the teachers in both partners related to improving the ...
Rochmad Rochmad, Arief Agoestanto, Muhammad Kharis   +2 more
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source