Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Bulletin of the scientific laboratories of Denison University.
, 1885 Title varies slightly.Mode of access: Internet.Official organ of: Denison Scientific Association ...
Denison Scientific Association. +1 more
core
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Strengthening innovation capacity of Nigerian agricultural research organizations: [PDF]
Strong agricultural research and development (R&D) is crucial for improving agricultural productivity and efficiency, which in turn both lead to agricultural development, food security, and poverty reduction.
Ragasa, Catherine +3 more
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Study on Population Carrying Capacity of Cultivated Land Based on Production Capacity
Shuitu baochi yanjiu, 2010 In order to provide a scientific basis for regional resources allocation and population policies in the new round of land-use planning revision,the paper aims to explore the scientific method of calculating the population carrying capacity of the method ...
ZHANG Xiao-yan +5 more
doaj
Strategy to Improve Scientific and Technological Innovation Capacity [PDF]
Proceedings of the 2017 International Conference on Applied Mathematics, Modelling and Statistics Application (AMMSA 2017), 2017 Feng Qian, Li Yang
openaire +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Capacity development for agricultural biotechnology in developing countries: Concepts, contexts, case studies and operational challenges of a systems perspective. [PDF]
There are divergent views on what capacity development might mean in relation to agricultural biotechnology. The core of this debate is whether this should involve the development of human capital and research infrastructure, or whether it should ...
Hall, Andy, Dijkman, Jeroen
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Capacity And Capacity Utilization In Fishing Industries
, 2003 The definition and measurement of capacity in fishing and other natural resource industries possess unique problems because of the stock-flow production technology, in which inputs are applied to the natural resource stock to produce a flow of output. In
Squires, Dale, Kirkley, James E.
core +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source