Results 111 to 120 of about 482,768 (286)

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

Reviewing, Reviewers and the Scientific Enterprise

Despite their critical importance to the scientific enterprise, reviewers receive no formal training and reviewing has become a skill that they pick up through trial and error.
Amanor-Boadu, Vincent
core  

Challenges for improving consensus reaching process in collective decisions

, 2007
The majority rule is frequently presented as a cornerstone of any democratic society, guiding many group decision-making processes where final decision requires the agreement of more than half the people involved.
Martínez, L., Montero De Juan, Francisco Javier   +1 more
core   +1 more source

A horizon scan for improving pesticide management and governance in the great barrier reef catchment

Frontiers in Environmental Science
The current policy environment for improving catchment pesticide water quality entering Australia’s Great Barrier Reef lagoon is based around Scientific Consensus Statement processes, which utilise systematic scientific literature reviews to develop ...
Aaron M. Davis, Steve Attard, Lawrence Di Bella, Evan Shannon, Rob Sluggett, Rob Milla, Emilie Fillols   +6 more
doaj   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Reputation-Based Consensus Protocol for Blockchain-Based Scientific Workflow Provenance

, 2023
A scientific workflow consists of ordered, non-linear tasks connected by their inputs and outputs. Provenance records play a crucial role in documenting the history of these scientific workflows, including data origin, analysis stages, parameters used ...
Williams, Skarlet, Dagher, Gaby, Miller, Matthew, Long, Min   +3 more
core  

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

Recommendations for the prevention of fragility fractures: a consensus from international experts and Ibero-American scientific societies

Purpose To develop a multidisciplinary consensus outlining key recommendations to prevent fragility fractures and improve care through coordinated efforts across healthcare sectors.
Bastida Calvo, José Carlos, Baixaulí García, Francisco, Condorhuamán Alvarado, Patricia Ysabel, Naranjo Hernández, Antonio, Neyro Bilbao, José Luis, Santiñá Vila, Manuel, Baquero Úbeda, José Luis, Aldecoa Álvarez Santullano, César, Micó Pérez, Rafael Manuel, Mur Molina, Blanca, Tarazona Santabalbina, Francisco José, Palacios Gil Antuñano, Santiago, Soto Bonel, José, Cuadra Llopart, Leonor, Ojeda Thies, Cristina, Cortés Berdonces, María, Cassinello Ogea, Concepción, Sáez López, Pilar, Giner García, Mercé, Arboiro Pinel, Rosa, Fernández Martínez, Nuria   +20 more
core   +1 more source

Stakeholder Consensus on Conservation Priorities Across Scientific, NGO, and Governmental Sectors

Conservation Letters
Understanding stakeholder perception is crucial for developing effective conservation strategies. Nevertheless, it is usually unclear which aspects are favored by different actors involved in environmental management.
Juan A. Hernández‐Agüero, Peter H. Verburg, Camille Magneville, Manuel Cartereau, Elysa Silva, Agathe Leriche, Jens‐Christian Svenning, Olga Tzortzakaki, Gianluigi Bacchetta, Federico Riva   +9 more
doaj   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source