Results 41 to 50 of about 3,110,040 (260)

Harmonizing quality measures of FAIRness assessment towards machine-actionable quality information

open access: yesInternational Journal of Digital Earth
FAIR Principles are a set of high-level guidelines for sharing digital resources. The growing global adoption of the FAIR Principles by policymakers, funders, and organizations compels data professionals, projects, and repositories to demonstrate the ...
Ge Peng   +11 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

The Geospatial Data Cloud: An Implementation of Applying Cloud Computing in Geosciences

open access: yesData Science Journal, 2014
The rapid growth in the volume of remote sensing data and its increasing computational requirements bring huge challenges for researchers as traditional systems cannot adequately satisfy the huge demand for service.
Xuezhi Wang   +3 more
doaj   +1 more source

A comprehensive integrated dataset on Brazilian health facilities: from 2005 to 2021

open access: yesBMC Research Notes, 2023
Objectives The National Registry of Healthcare Facilities is a system with the registry of every healthcare facility in Brazil with information on the capacity building and healthcare workforce regarding its public or private nature.
Rebecca Salles   +20 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Bibliometric approach for innovations analysis in the field of Disaster Risk Reduction

open access: yesBerkala Ilmu Perpustakaan dan Informasi, 2022
Introduction. This study demonstrates the use of bibliometric methods for innovation analysis, using the field of Disaster Risk Reduction (DRR) in Indonesia as a case study.
Noorika Retno Widuri   +5 more
doaj   +1 more source

Recording Scientific Data

open access: yes, 2022
AbstractThe core of a scientific manuscript is the new data the authors are presenting. These core data should be presented with an appropriate degree of precision that does not go distractingly overboard. Readers are particularly interested in the numbers associated with each group and how these compare.
Stephen Luby, Dorothy L. Southern
openaire   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Data trace as the scientific foundation for trusted metrological data: a review for future metrology direction [PDF]

open access: yesPeerJ Computer Science
In the context of the digital transformation of metrology, ensuring the trustworthiness and integrity of measurement data during its generation, transmission, and storage—i.e., trustworthy detection of measurement data—has become a critical challenge ...
Zhanshuo Cao   +5 more
doaj   +2 more sources

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