Results 241 to 250 of about 4,013,520 (312)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Assessing Science Practices in Undergraduate Chemistry Laboratories: Why We Need to Do Betterand How We Should. [PDF]

J Chem Educ
Bapu Ramesh V, Seery MK, Cole R.
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Psychology should move from selective allyship to empowered actions to tackle global crises. [PDF]

Commun Psychol
Kutlaca M, Radke HRM, Uluğ ÖM.
europepmc   +1 more source

The Nature of Knowledge and Epistemic Interests of Radiography Science-An Analysis of Doctoral Dissertations Using Critical Normative Epistemology Framework. [PDF]

Scand J Caring Sci
Sanna T, Helena LK, Mervi S, Eija M.
europepmc   +1 more source

What do the differences and commonalities in doctoral dissertation acknowledgments across disciplines reveal? [PDF]

PLoS One
Yang K, Han J, Zhuang H.
europepmc   +1 more source

Emerging Neisseria meningitidis ST-1466 and ST-11026 as urogenital pathogens in China. [PDF]

BMC Infect Dis
Zhu Z, Bao Y, Zhang Z, Ye L, Ke Y.
europepmc   +1 more source

Impact assessment of the ophthalmology discipline construction project at Tianjin Medical University Eye Hospital. [PDF]

Health Res Policy Syst
Sun H, Li X, Yu X, Li F, Zhang T, Song J, Du Y, Liu H.   +7 more
europepmc   +1 more source