Results 51 to 60 of about 735,878 (311)

A Project Portfolio Management model adapted to non-profit organizations [PDF]

open access: yes, 2016
As they strive towards greater professionalism in carrying out their activities, non-profit organizations (NPOs) have begun paying attention to project management.
de Freitas, Henrique M R   +2 more
core   +3 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Sustainable Fisheries & Coastal Zoning in Montserrat: Legal & Institutional Assessment of Authorities & Approaches [PDF]

open access: yes, 2015
In February 2015, the Government of Montserrat and the Waitt Institute signed a memorandum of understanding to launch Blue Halo Montserrat, a comprehensive ocean and coastal management project with a goal of sustainable management of Montserrat's ocean ...
Kathryn mengerink, Read D. Porter
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Analysis of articles supported by nursing management fund and published in 12 core nursing journals from 2012 to 2014

open access: yesHuli yanjiu, 2017
Objectie:To understand the scientific status of nursing management fundsupported research in China from 2012 to 2014 and its existing problems,in order to proide a basis for promoting the deelopment of nursing management research in China.Methods: The ...
董丽娟, 程金莲, 陈琼
doaj  

Spatial‐environmental predictors of crop raiding and livestock predation in the communal area around Doma Safari Area of Zimbabwe

open access: yesEcological Solutions and Evidence
Mapping hotspots of negative human–wildlife interactions and understanding environmental drivers of crop raiding and livestock predation risk provide a foundation to work towards coexistence between people and wildlife. In this study, the binomial linear
Knowledge Kudakwashe Mawere   +6 more
doaj   +1 more source

EURAD − the European Joint Programme for research on radioactive waste management between EU members states national programmes

open access: yesEPJ Nuclear Sciences & Technologies, 2020
For more than 40 years, considerable scientific and technical knowledge has been acquired in Europe in the field of radioactive waste management, both for near-surface disposal and geological disposal.
Garcia Marie   +2 more
doaj   +1 more source

Models of financing research: public funding mechanisms for universities in Flanders [PDF]

open access: yes, 2015
This paper gives an overview of the models of financing research at universities in Flanders, Belgium. The Flemish government installed parallel mechanisms to distribute financial means for scientific research at the universities: research is supported ...
De Craemer, Dirk
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Challenges and Prospects of Developing Light Industry in Russia

open access: yesВестник Российского экономического университета имени Г. В. Плеханова
Today enterprises of light industry face serious problems arising due to competition with Asian companies, problems with investment and staff. Comparative analysis of key figures of light industry in Russia and China shows considerable backwardness of ...
D. V. Khrulkov
doaj   +1 more source

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