Results 81 to 90 of about 728,635 (308)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Special Libraries, July 1978 [PDF]
, 1978 Volume 69, Issue 7https://scholarworks.sjsu.edu/sla_sl_1978/1005/thumbnail ...
Special Libraries Association
core +1 more source
Comparative Experience of the Effectiveness of Financing Small Enterprises [PDF]
, 2018 The article considers existing criteria of estimation of financing subjects of small business in Germany and Russia for raising its effectiveness for Russia. We analyzed main directions and mechanisms of state support in these countries.
Huszar, E. (Elisabeth)
core +2 more sources
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Features of the management of the territories of National nature parks
Zemleustrìj, Kadastr ì Monìtorìng Zemelʹ, 2023 According to the data of the State Cadastre, at the beginning of 2021, the nature reserve fund counted 8,633 territories and objects with a total area of 4.1 million hectares, which was 6.8% of the country's area.
M. Shershun, T. Mykytyn
doaj
Journal of EcohumanismThe article examines the application of Artificial Intelligence (AI) in managing scientific and educational projects funded by the KEGA and VEGA grant schemes in Slovakia. The objective is to analyse how AI contributes to more efficient management of project processes, including the initiation, planning, implementation, monitoring, and closure of ...
Kateřina Bočková +2 more
openaire +1 more source
New Zealand freshwater management and agricultural impacts [PDF]
In New Zealand, it is increasingly recognised, including by government, that water resource allocation and water quality are issues of national importance.
Cullen, Ross +2 more
core +1 more source
New quality of financial institutions and business management [PDF]
, 2020 Economic processes in the world are characterized by a high level of dynamism, change and innovative approaches to addressing key issues in nowadays.
Kraus, Kateryna +2 more
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Special Libraries, September 1966 [PDF]
, 1966 Volume 57, Issue 7https://scholarworks.sjsu.edu/sla_sl_1966/1006/thumbnail ...
Special Libraries Association
core +1 more source