Results 201 to 210 of about 80,748 (261)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

AI is turning research into a scientific monoculture. [PDF]

open access: yesCommun Psychol
Traberg CS   +2 more
europepmc   +1 more source

Combating converging crises: The role of universities in global health, climate, and equity. [PDF]

open access: yesJ Clim Chang Health
Ratevosian J   +20 more
europepmc   +1 more source
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Scientific Inquiry

Journal for Specialists in Pediatric Nursing, 2007
Scientific Inquiry provides a forum to facilitate the ongoing process of questioning and evaluating practice, presents informed practice based on available data, and innovates new practices through research and experimental learning.
JoAnne M. Youngblut, Dorothy Brooten
  +4 more sources

The Logic of Scientific Inquiry

Synthese, 1974
Is methodological theory a priori or a posteriori knowledge? It is perhaps a posteriori improvable, somehow. For example, Duhem discovered that since scientists disagree on methods, they do not always know what they are doing.
openaire   +2 more sources

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