Results 71 to 80 of about 4,908,769 (289)

Challenges and Future Directions in Assessing the Quality and Completeness of Advanced Materials Safety Data for Re‐Usability: A Position Paper From the Nanosafety Community

open access: yesAdvanced Sustainable Systems, EarlyView.
Nanosafety data provide a guiding example for establishing best practices in data management, aligning with FAIR principles and quality criteria. This review explores existing quality assessment approaches for reliability, relevance, and completeness, emphasizing the need for harmonization and adaptation to nanomaterials and advanced materials. The aim
Verónica I. Dumit   +43 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

The reporting of statistical significance in scientific journals [PDF]

open access: yes
Scientific journals in most empirical disciplines have regulations about how authors should report the precision of their estimates of model parameters and other model elements.
Jan M. Hoem
core   +3 more sources

Avaliação pelos pares nas revistas de comunicação: visão dos editores, autores e avaliadores

open access: yesPerspectivas em Ciência da Informação
O estudo verificou como ocorre a avaliação de originais nas revistas de Comunicação, de acordo com 13 editores, autores e avaliadores de sete revistas.
Ida Stumpf
doaj   +1 more source

Between fetishism and survival : is the scientific article an academic commodity? [PDF]

open access: yes, 2007
This article discusses the possible meanings of the intense prevailing concern in academic circles over the notion of research productivity, as reflected in an excess number of articles published in various scientific journals.
Castiel, Luis D., Sanz-Valero, Javier
core  

The influence of online posting dates on the bibliometric indicators of scientific articles [PDF]

open access: yes, 2017
This article analyses the difference in timing between the online availability of articles and their corresponding print publication and how it affects two bibliometric indicators: Journal Impact Factor (JIF) and Immediacy Index.
Cordon-Garcia, Jose-Antonio   +2 more
core   +4 more sources

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

open access: yesAdvanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that preces the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl   +27 more
wiley   +1 more source

The Arts of Persuasion in Science and Law: Conflicting Norms in the Courtroom [PDF]

open access: yes, 2009
Epistemology is important in the debate about science and technology in the courtroom. The epistemological issues and the arguments about them in the context of scientific and technical evidence are now well developed.
Kritzer, Herbert M.
core   +1 more source

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu   +9 more
wiley   +1 more source

The Age‐Dependent Resident Myonuclear Multi‐Omic Response to an Acute Skeletal Muscle Hypertrophic Stimulus in Mice

open access: yesAdvanced Science, EarlyView.
Resident myonuclei are the molecular “control centers” for large multinuclear muscle fibers. It is presumed that, with aging, these control centers become compromised and contribute to delayed or blunted muscle adaptive potential. This study is a detailed roadmap that exposes how young versus aged myonuclei respond to a hypertrophic loading stimulus ...
Pieter J. Koopmans   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy