Results 31 to 40 of about 1,366,937 (260)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Scientific Knowledge Management in Socio-environmental Systems Context
tripleC: Communication, Capitalism & Critique, 2011 This article focuses on the efficiency of scientific knowledge involved in the context of managing a particular socio-environmental as that composed by Amazon.
Luiza Beth Nunes Alonso +3 more
doaj +1 more source
Expert knowledge as a social phenomenon: theoretical and mythodological analysis
Наука. Культура. Общество, 2022 The transformations of modern society with its rapid informatization and digitalization form a new social demand for analyzing present and future. A figure of an expert appears more and more often as a producer of special expert knowledge in public ...
Alexander A. Koshelev +1 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
THE FOUNDATIONS OF KNOWLEDGE DECENTRALIZATION – A CONDITION FOR FREEDOM [PDF]
Societate şi Politică, 2011 Within the economic space or within the social spacethe knowledge is essentially a dispersed one, and through it we must understanda practical knowledge peculiar to individual circumstances.
Bogdan ŞTEFANACHI
doaj
Teaching and learning nature of scientific knowledge: Is it Déjà vu all over again?
Disciplinary and Interdisciplinary Science Education Research, 2019 This review traces the history of research on the teaching and learning of nature of scientific knowledge (NOSK), and its implications for curriculum and instruction. Initially, the complex rubric of NOSK is clearly conceptualized, while recognizing that
Norman G. Lederman, Judith S. Lederman
doaj +1 more source
Teosofi: Jurnal Tasawuf dan Pemikiran Islam, 2017 The article discusses the Integrated Twin Towers paradigm introduced by Sunan Ampel State Islamic University (UIN) Surabaya. The paradigm promulgates an integrated pattern of Islamic studies and sciences as its epistemological basis and philosophical ...
M. Syamsul Huda
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Dynamic frame as a structure for scientific knowledge representation [PDF]
Актуальные проблемы филологии и педагогической лингвистики, 2019 This paper presents the features of the dynamic frame verbalization as one of the ways of ordering scientific knowledge. The scientific discourse or text under study are considered as areas in which the terms are directly included in real professional ...
Klyoster Anna M., Shnyakina Natalia Ju.
doaj +1 more source