Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
How to write a perfect scientific manuscript [PDF]
Catchy and provocative manuscript titles, no clear study objectives, no data on a rationale for sample sizes, the failure to define study variables, redundant summary data, poor presentation of data distribution, survival curves without naming the number of patients at risk—these are just a few examples of the shortcomings in the manuscripts that the ...
openaire +3 more sources
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The ChatGPT conundrum: Human-generated scientific manuscripts misidentified as AI creations by AI text detection tool. [PDF]
Rashidi HH +4 more
europepmc +1 more source
СТРУКТУРНІ ТА СТИЛІСТИЧНІ ОСОБЛИВОСТІ ПАМ’ЯТОК НАУКОВО-ПРАКТИЧНОГО ЖАНРУ XVIII СТ. (Structural and stylistic peculiarities of the memorial of scientific-practical Genre XVIII century.) [PDF]
Порівняльний типологічний аналіз рукописів календарів XVIІІ ст. дозволив дослідити структуру, виділитий охарактеризувати специфічні стилістичні особливості пам’яток науково-практичного жанру.
Файчук, Т. (T. Faichuk)
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Effective Use of Hedging in Scientific Manuscripts: Advice to Non-Native English-Speaking Researchers. [PDF]
Kojima T, Popiel HA.
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Prof. David L. Schriger: Guidelines for Presenting Tables and Figures in Scientific Manuscripts. [PDF]
Du KJ +5 more
europepmc +1 more source

