Results 131 to 140 of about 359,912 (292)

Assembling the heritage of scientific manuscripts in scientific libraries of vilnius in 1990-2010.

, 2014
Three scientific libraries of Vilnius have been long assembling the heritage of scientific manuscripts in their Manuscript Departments. These libraries are the Vilnius University Library, the Wroblewski Library of the Lithuanian Academy of Sciences and ...
Navardauskaitė, Rūta,
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Historical and scientific analysis of Iranian illuminated manuscripts and miniature paintings

, 2009
The present study aims to identify the materials and techniques used in Persian illuminated manuscripts and miniature paintings and its major significance in comparison with Indo-Iranian and Mughal paintings.
Barkeshli, Mandana
core  

The Ottoman Manuscripts and The Projects of Digitizing The Manuscripts in Turkey [PDF]

, 2008
Manuscripts are written memories lighting the scientific development of the period in which they were created. They are also works of art having unique examples of calligraphy, miniature, marbling and bookbinding arts.
Polat, Coşkun, Odabaş, Z. Yonca, Odabaş, Hüseyin   +2 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Bibliography of catalogues of Algerian manuscripts: a statistical and Descriptive Study

Akofena
: This study is a comprehensive survey of the efforts made in cataloguing Arabic manuscripts in Algeria, by tracing the history of these efforts from the first initiatives undertaken by Algerian researchers and some orientalists, to the institutional ...
Laid HADJ KOUIDER
doaj   +1 more source