Results 61 to 70 of about 359,912 (292)

Manuscripts Not Accepted for Publication

open access: yes, 2022
The Allaire Data project is conducted rigrously according to the scientific method (for understanding of the scientific method, see for example the Science or Not? website).
John Kosinski (691871)
core   +1 more source

ANALYSIS OF MANUSCRIPTS ON ETHICS IN SCIENTIFIC RESEARCH AT SCIENTIFIC ELECTRONIC LIBRARY ONLINE (SCIELO)

open access: yesRevista Latinoamericana de Bioética, 2015
La ética en la investigación se convirtió en un tema central en relación con la globalización del desarrollo científico, sobre todo cuando se refieren a las condiciones socioeconómicas de los países que participan como socios en los protocolos de ...
Flávia Squinca   +2 more
doaj   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Chautauqua Literary and Scientific Circle - Bowling Green, Kentucky (MSS 700)

open access: yes, 2020
Finding aid only for Manuscripts Collection 700. Minute books, yearbooks, and sundry other items from the Chautauqua Literary and Scientific Circle, a women’s literary club in Bowling Green ...
Folklife Archives, Manuscripts &
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Formatting Open Science: agilely creating multiple document formats for academic manuscripts with Pandoc Scholar [PDF]

open access: yesPeerJ Computer Science, 2017
The timely publication of scientific results is essential for dynamic advances in science. The ubiquitous availability of computers which are connected to a global network made the rapid and low-cost distribution of information through electronic ...
Albert Krewinkel, Robert Winkler
doaj   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Number and Measurement in Anglo-Saxon Christian Culture: Editions and Studies of Numerical Notes in Eight Anglo-Saxon Manuscripts, c.800-c.1150 [PDF]

open access: yes, 2012
This two-part thesis explores aspects of Anglo-Saxon number culture through a detailed examination of numerical encyclopaedic notes. The first part (Chapters I-III) is an edition of seventy-two notes transmitted in eight Anglo-Saxon manuscripts.
Walbers, Birte
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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