Results 251 to 260 of about 8,315,700 (303)

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Mechanism of K63-linked polyubiquitin recognition and cleavage by the BRCA1-A complex. [PDF]

open access: yesNat Commun
Foglizzo M   +12 more
europepmc   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Validation of Wound Assessment Instruments Across Brazilian Clinical Contexts: Protocol for a Scoping Review. [PDF]

open access: yesJMIR Res Protoc
Nunes CAV   +24 more
europepmc   +1 more source

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