Mapping Knowledge Domains is a special supplement to the April 6 issue of the <em> Proceedings of the National Academy of Sciences </em> (PNAS). Many of the articles raise OA issues, either by tracking OA collections or making use of OA literature as data to learn about scientific trends.
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A comparative study of thematic mapping and scientific visualization [PDF]
Thematic mapping and scientific visualization are two dedicated areas for visualizing a wide range of domain-specific data sets. From a general perspective, thematic mapping and scientific visualization reveal large overlaps in terms of visualization methods.
Linfang Ding, Liqiu Meng
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Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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Smart City Knowledge Mapping: An Analytical Approach Using VOSviewer [PDF]
Analyzing the Smart City Knowledge Map with VOSviewer is necessary because it helps identify research patterns, thematic clusters, and emerging trends in this field.
Hafez Mahdnejad
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
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Analysis of the Scientific Map of Brand Positioning Research Based on the Scopus Citation Database (1975-2023) [PDF]
Purpose: Considering the importance of brand positioning for any business and the growing trend of research in this field, the necessity of conducting scientific studies is fully felt.
Moslem Rezai +2 more
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Scientific Maps: Methods and Techniques
Scientific publications are rapidly developing as a result of science domains development. Therefore tracing research trends in various domains of science has become a challenge. In fact, limitations of conventional methods of analysis of various domains of science and their weaknesses in representing a comprehensive view of knowledge, has led ...
Ramezani, Hadi +2 more
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
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Mapping the Scientific Map and Analyzing the Co-Occusrrence of the Concept of the Digital Ecosystem with a Management Approsach on the Web of Science [PDF]
Purpose: With the growing complexity of organizational environments in both the private and public sectors, the need for inter-organizational cooperation has become increasingly important.
Mahdi Hedayatfar, Ayoub Mohammadian
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Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
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