Results 71 to 80 of about 159,088 (249)
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
FISH-AI_WP2_2.2_D07_Minutes annual meetings back-to-back with scientific societies
, 2022 This dataset collects the annual meetings of the consortium where members meet to discuss progress and opened ...
Camin, Federica
core +1 more source
Dermatologica Sinica, 2017 Background/Objectives: The publication rate (PR) of congress abstracts externalizes the reputability and scientific value of meetings. The purpose of this study is to analyze the PRs of Australasian College of Dermatologists (ACD) meetings.
Aylin Ozturk Meral, Didem Didar Balci
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
The Minutes of the Meetings of the Commission of Archaeology in Vilnius: 1856–1858
Bibliotheca Lituana, 2012 The Museum of Antiquities and Interim Commission of Archaeology in Vilnius which was the most significant educative scientific and cultural centre of that time both in Vilnius and Lithuania was founded in 1855 and was active for nearly a decade.
Žygintas Būčys
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Scientific societal meetings as opportunities for science eduation in developing countries [PDF]
, 2009 Brazilian Scientific productivity presented a remarkable growth during the last two decades, as inferred by the number of articles published by Brazilian authors. The number of Brazilian secondary students also grew sharply.
Longo Marques, M. +3 more
core
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source