Results 231 to 240 of about 36,943,093 (318)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Correction: An improved GC-MS-SIM analytical method for determination of pendimethalin residue in commercial crops (leaf and soils) and its validation. [PDF]

PLoS One
Paul A, Majumder S, Prasad LK, Madhav MS, Johnson N, Padmaja K, Singh S.   +6 more
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

A multicriteria quality evaluation method for organized scientific research considering heterogeneous information. [PDF]

Sci Rep
Wang C, Zhang L.
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Correction: The effects of the secondary metabolites of the citrus endophytic fungus Nemania sp. LJZ-Y-11 on the citrus canker disease-causing pathogen Xanthomonas Citri subsp. Citri. [PDF]

BMC Microbiol
Chen X, Li Q, Yao J, Huang L, Lu R, Deng Z, Luo H, Deng Y, Xu X.   +8 more
europepmc   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Clinical evaluation and comparative study of a fully automated erythrocyte osmotic fragility analysis system based on scatter turbidimetry. [PDF]

Sci Rep
Ma L, Huang Y, Chen T, Yang F, Wang X, Xiong F, Tang J, Zhang S, Gao Y.   +8 more
europepmc   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Correction: Research on multi-physical field coupling modeling and multi-condition dynamic load capacity evaluation of oil-immersed transformers. [PDF]

Sci Rep
Zhu H, Xiaohang R, Guobo Y, Chunlei Y, Xiaoqian B.   +4 more
europepmc   +1 more source