Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Scientific production on instruments adapted to native languages in the Peruvian context. [PDF]
Phoco-Arhuiri RM +2 more
europepmc +1 more source
Bibliometric analysis of the worldwide scientific production on COVID-19 infection and cerebrovascular disease. [PDF]
Palomino-Leyva C +5 more
europepmc +1 more source
Institutional repositories and scientific production in Portuguese universities: current panorama
Ramos, Cecília da Conceição Reis +1 more
openalex +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Scientific Production on Chemical Burns: A Bibliometric Analysis (1946-2024). [PDF]
Cueva-Ramírez JE +3 more
europepmc +1 more source
Examination of Scientific Production on Badminton: A Content Analysis
Mehmet Akarsu, Yahya Doğar
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
A bibliometric approach to worldwide scientific production of familial hypophosphataemic rickets in Scopus (2000-2022). [PDF]
Hernández-García F +6 more
europepmc +1 more source

