Results 201 to 210 of about 586,771 (255)

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

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Scientific Progress

2015
Abstract We deal with the problem of verisimilitude, a notion which, roughly speaking, tries to capture how close a scientific theory is to the truth. Our starting philosophical basis is Evandro Agazzi’s approach and his view on scientific objectivity which relies on his particular meaning of ‘partial truth’. By following an epistemological approach to
Vincenzo Fano, Giovanni Macchia, Fano Vincenzo   +2 more
exaly   +4 more sources

Scientific progress as increasing verisimilitude

Studies in History and Philosophy of Science Part A, 2014
According to the foundationalist picture, shared by many rationalists and positivist empiricists, science makes cognitive progress by accumulating justified truths. Fallibilists, who point out that complete certainty cannot be achieved in empirical science, can still argue that even successions of false theories may progress toward the truth.
Ilkka Niiniluoto
exaly   +3 more sources

Scientific progress

SynthÈse, 1980
Ilkka Niiniluoto, Niiniluoto Ilkka
exaly   +3 more sources

Constants and scientific progress

Physiological Genomics, 1999
Scientists like constants (a personal favorite is Avogadro's number). It is no wonder, because not only does defining a constant represent a major scientific breakthrough, but as human beings we like things we can rely on, things that stay the same and that bring us consistency, stability, and a ...
V, Dzau, M, Frank, M, Reich, M J, Austin, R, Aebersold, A, Cowley, D, Housman, R, Mulligan, R, Rosenberg   +8 more
openaire   +2 more sources

Is there scientific progress?

2023
Abstract Claudius Ptolemy and Galen of Pergamum made contributions to scientific and medical thought and practice that remained foundational for over 1,000 years. Ptolemy and Galen regarded themselves as innovators and as educators who were philosophically astute, building on the work of their predecessors and synthesizing information ...
openaire   +1 more source

Predictive models of scientific progress

Information Storage and Retrieval, 1971
Abstract Progress in science is essentially determined by the stimulating effects of information accumulation and transfer. Hence dynamic characteristics of information flow together with the structural properties of the flow network in the society should be indicative of the major thrusts of science progress as well as of its rate of development ...
Pranas Zunde, Vladimir Slamecka
openaire   +1 more source

Mathematics, Indispensability And Scientific Progress

Erkenntnis, 2001
Evaluation de l'argument platonicien de l'indispensabilite des objets mathematiques, fonde sur le naturalisme de Quine, a la lumiere de la conception nominaliste des theories scientifiques. Mesurant le role des mathematiques dans la decouverte et le developpement de la science, l'A. montre que les vertus philosophiques du nominalisme ne suffisent pas a
openaire   +2 more sources