Results 21 to 30 of about 303,502 (252)
Phrenologizing Opera Singers: The Scientific “Proofs of Musical Genius” [PDF]
19th-Century Music, 2015 In some descriptions from the first half of the nineteenth century, scientific categories are used syncretically to explain opera singers' talents, including their innate and acquired dispositions, and their effects on audiences. Phrenology sought to read on the surface of skulls the developments of cerebral zones that corresponded to various instincts,
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
SOCIO-COMMUNICATIVE NATURE OF SCIENTIFIC ACTIVITY
Вестник Северо-Кавказского федерального университета, 2022 The item shows socio-communicative basics of the modern scientific activity. There is proof offered to the idea that sociological views on scientific communications allow rethinking the traditional epistemological ideas regarding scientific subjectivity ...
Elena A. Sergodeeva
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Role of Scientific Evidence in the Adjudication of Dispute for Restoration of Burned Forest and Land [PDF]
E3S Web of Conferences, 2020 One of the objectives of the adjudication of forest and land fire dispute is to restore the burned forests and land. However, evidencing aspect of forest and land fire cases in the judicial settlement is often challenging and the scientific evidence is ...
Aminudin Cecep +3 more
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
“Homeopathy is not placebo effect”: proof of the scientific evidence for homeopathy
Revista Da Associação Médica BrasileiraTeixeira Mz
exaly +4 more sources
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
RECONSTRUCTION OF SCIENTIFIC INVESTIGATION IN INDONESIA
Jurnal Pembaharuan Hukum, 2018 The purpose of this study is to analyze the process of scientific investigation, the empowerment of scientific investigation by investigators, obstacles faced and finding scientific investigation based ideal of justice.
Teguh Prihmono
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SCIENTIFIC PROOF AND RELATIONS OF LAW AND MEDICINE
Annals of Internal Medicine, 1943 Excerpt The anvil of the law has always resounded to the striking iron of science. Some tough metal has been beaten out there, sometimes into curious shapes, and few members of the populace can hav...
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