Results 101 to 110 of about 715,320 (274)

Indicadores altmétricos y de citación en la producción científica en ScienceOpen: estudio descriptivo para Brasil, España y Portugal. [PDF]

, 2018
Objective. To describe evidences of certain bibliographic issues and their influence on altmetrics and bibliometrics indicators, considering a set of Brazilian, Spanish and Portuguese articles. Design/Methodology/Approach.
Ferreira de Araújo, Ronaldo, Travieso Rodríguez, Críspulo   +1 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Impact and productivity of Latin American publications about mathematics education

Biblios, 2015
More than a century room recently they have been carrying out, frequently annual Educational Mathematics Latin American Meetings (RELME) and the works presented in the event, after a revision for even of experts, the ALME is published (Latin American ...
Aida Maria Torres-Alfonso, María Josefa Peralta-González, Anamarys Toscano-Menocal   +2 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Szientometrische Analyse der wissenschaftlichen Zeitschriftenliteratur zum Thema „ökologische Landwirtschaft“ [PDF]

, 2013
In this literature review we use basic scientometric indicators to analyze a corpus of 2,801 peer-reviewed scientific journal articles on organic agriculture obtained from the “ISI – Web of Science” databases and compare their dynamic with the general ...
Siegmeier, Torsten
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

SCIENCE AND TECHNOLOGY INDICATORS IN THE AGRICULTURAL SIENCE SECTOR IN BRAZIL: PUBLIC INVESTMENT AND SCIENTIFIC AND TECHNICAL PRODUCTIVITY

Revista Gestão Inovação e Tecnologias, 2018
Trata-se de evidenciar como os esforcos do governo sao revertidos em produtividade cientifica e tecnica no setor de ciencias agrarias no pais atraves da analise de diferentes indicadores de ciencia e tecnologia, tanto de insumos (input) como de produtos do sistema nacional de inovacao (output).
C. Hasner, E. Winter
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Normalization and Valuation of Research Evaluation Indicators in Different Scientific Fields

Journal of Information Science Theory and Practice, 2016
Given the difference in research performance in various scientific fields, this study aims to weight and valuate current indicators used for evaluation of scientific productions (publications), in order to adjust these indicators in comparison to each ...
Chakoli, Abdolreza Noroozi, Ghazavi, Roghayeh   +1 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source