Results 181 to 190 of about 204,501 (304)

Refusal and Aporia: At the Limits of Anthropological Knowledge

open access: yesAmerican Anthropologist, EarlyView.
ABSTRACT As anthropologists increasingly take up refusal, opacity, and other forms of resistance to surveillance and subjugation, this paper questions what implications this has for the discipline in practice. Considering anthropology's enduring centrality in defining what it means to be human, including the various ways that this category has been ...
Cory‐Alice André‐Johnson
wiley   +1 more source

Researching Rupture: Engaged and Ethical Research on Extreme Nature–Society Disruption

open access: yesAntipode, EarlyView.
Abstract Global escalation in social and environmental disruption raises crucial methodological and ethical questions for researchers working in impacted communities. Interpretive social science and humanities research can make visible the experiences of those living through socio‐ecological “rupture”.
Sango Mahanty   +5 more
wiley   +1 more source

The Credibility of Bioethics After the Gaza Genocide

open access: yesBioethics, EarlyView.
ABSTRACT Between October 2023 and January 2025, the Israeli military's sustained attacks on Gaza resulted in an estimated 186,000 deaths and the systematic destruction of healthcare infrastructure. Despite the professed commitment to human dignity, justice, and the minimization of suffering within bioethics, major institutions and scholars in the field
Maide Barış   +4 more
wiley   +1 more source

“Yet the Problem Remains”: Why Genetic Determinism Still Haunts Biomedical Research

open access: yesBioethics, EarlyView.
ABSTRACT After the horrors of the Holocaust and its connections to eugenics were revealed to the world, many post‐war population geneticists sought to establish rhetorical distance from the Nazi's state‐led campaigns, without abandoning their belief that actively shaping the population's genetics would produce a prosperous society.
Christopher R. Donohue, Ian A. Myles
wiley   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

open access: yesBritish Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi   +10 more
wiley   +1 more source

Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β‐arrestin recruitment and the discovery of an allosteric agonist

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lactate, historically viewed as a metabolic by‐product, has emerged as a signalling molecule via the G protein–coupled receptor Hydroxycarboxylic Acid Receptor 1 (HCAR1). The receptor is primarily expressed in adipocytes but also found in various other tissues.
Simon Lind   +6 more
wiley   +1 more source

Matsupexole: A novel nonergot dopamine receptor agonist with sustained efficacy in a rat model of Parkinson's disease and limited off‐target activity

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Dopamine receptor agonists, particularly targeting the dopamine D2L receptor (D2LR), have been used to treat Parkinson's disease (PD). However, valvular heart disease and somnolence, mainly caused by activating the serotonin 5‐HT2B receptor (5‐HT2BR) and dopamine D3 receptor (D3R), respectively, currently challenge their clinical
Takayuki Suzuki   +4 more
wiley   +1 more source

Mediating mechanisms in the discrimination - Mental health link among Mexican-origin adolescents: A latent growth curve mediation analysis. [PDF]

open access: yesDev Psychopathol
Park IJK   +8 more
europepmc   +1 more source

Youth‐Reported Strengths and Challenges in Illinois Child Welfare Residential Care: An Analysis of Qualitative Data From > 500 Youth

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT This study explores qualitative data capturing the strengths and challenges of residential care from the perspective of 512 youth in Illinois child welfare residential care in November 2018. Ninety percent of eligible youth participated in a Youth Experience of Care survey, with youth providing more negative than positive feedback about ...
Patricia Garibaldi   +5 more
wiley   +1 more source

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