Results 211 to 220 of about 204,003 (303)

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Exclusive research is bad science: the epidemiologic argument for diversity, equity, and inclusion in research. [PDF]

Int J Epidemiol
Daodu O, Kalenga Adejumo C, Ronksley PE, Belanger S, Ruzycki SM.   +4 more
europepmc   +1 more source

Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β‐arrestin recruitment and the discovery of an allosteric agonist

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lactate, historically viewed as a metabolic by‐product, has emerged as a signalling molecule via the G protein–coupled receptor Hydroxycarboxylic Acid Receptor 1 (HCAR1). The receptor is primarily expressed in adipocytes but also found in various other tissues.
Simon Lind, Shane C. Wright, Emilia Gvozdenovic, Kristina Nilsson, Kenneth L. Granberg, Michel Bouvier, Linda C. Johansson   +6 more
wiley   +1 more source

International Learning Initiative Part 2: Enhancing Antiracism Awareness Among Nursing Students in Sweden and the USA. [PDF]

Scand J Caring Sci
Odzakovic E, Raphael-Grimm T, Falck J, Hamed S, Lindblom J, Huus K, Björk M.   +6 more
europepmc   +1 more source

Matsupexole: A novel nonergot dopamine receptor agonist with sustained efficacy in a rat model of Parkinson's disease and limited off‐target activity

British Journal of Pharmacology, EarlyView.
Background and Purpose Dopamine receptor agonists, particularly targeting the dopamine D2L receptor (D2LR), have been used to treat Parkinson's disease (PD). However, valvular heart disease and somnolence, mainly caused by activating the serotonin 5‐HT2B receptor (5‐HT2BR) and dopamine D3 receptor (D3R), respectively, currently challenge their clinical
Takayuki Suzuki, Fumiki Oana, Masaki Oota, Yuma Handa, Osamu Kaminuma   +4 more
wiley   +1 more source

A latent measure of cultural racism and its association with US mortality and life expectancy. [PDF]

Nat Hum Behav
Akinyemiju T, Osazuwa-Peters OL, Brown TH, Ramos J, Jones S, Wilson LE, Krieger N.   +6 more
europepmc   +1 more source

Bias at the Bedside: A Comprehensive Review of Racial, Sexual, and Gender Minority Experiences and Provider Attitudes in Healthcare. [PDF]

Healthcare (Basel)
Carter EJR, Sagaribay R, Singh A, Evangelista LS, Kuhls DA, Pharr JR, Batra K.   +6 more
europepmc   +1 more source

Surgeon Regret and Shared Decision‐Making for Hepatopancreatobiliary Cancer: A Survey of Australia and New Zealand

ANZ Journal of Surgery, EarlyView.
Joshua G. Kovoor, John M. Kefalianos, Harleen K. Aulakh, Angad Singh, Vincent Lam, Vijayaragavan Muralidharan, Saxon Connor, Thomas J. Hugh   +7 more
wiley   +1 more source