Results 71 to 80 of about 5,759,874 (279)
A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu +17 more
wiley +1 more source
© the Editors and contributors 2004. All rights reserved.Rural issues are currently attracting unprecedented levels of interest, with the debates surrounding the future of 'traditional' rural customs and practice becoming a significant political concern.
Garland, J, Chakraborti, N
core +1 more source
Racism and Islamophobia: A Personal Perspective [PDF]
The article employs a subjective personal approach to show that new racisms are alive in the twenty-first century. Tracing my parents’ journey from India and Pakistan to Britain, it explores the political effects of the racism they and their children ...
Saeed, Amir
core +1 more source
TED1 Promotes the Assembly of SCFD3‐D14‐D53 to Reinforce Strigolactone Signaling in Rice
This study identifies TED1 as a positive regulator of strigolactones (SL) signaling in rice. The ted1 mutants display dwarfism and increased tillering with significantly reduced SLs sensitivity. Through its longer C‐terminal region, TED1 interacts with D53 and D14 to promote the assembly of SCFD3‐D14‐D53, thereby facilitating the efficient ...
Sheng Luo +22 more
wiley +1 more source
Covalently Linked Peptides and Membrane Potential Enable CyaA Segment Translocation
Using a newly developed Droplet Interface Bilayer‐Pipette assay, the authors show that two segments of the CyaA toxin cross membranes by distinct mechanisms. One segment translocates spontaneously, whereas the translocation of the other depends on membrane potential.
Gaia Scilironi +9 more
wiley +1 more source
Highlights: - Explores a historical and civic controversy surrounding Linnaeus’s place in the history of scientific racism through a large-scale classroom intervention in upper secondary history education.
Olle Nolgård +4 more
doaj +1 more source
1 p. : ill. ; 27 cmPublic flyer announcing the upcoming 'Rally Against Racism' set to occur on 11 May 1995 at 8 p.m.
Author unknown
core +1 more source
Covenants mapped as of Mar. 2 2023Other title Milwaukee County racial covenants, early results Notes This map shows the progress to date of the Mapping Racism and Resistance project in identifying housing deeds that included racial covenants.
Mapping Racism and Resistance
core
SOX2 upregulates KAT7 in glioma stem cells, where KAT7 deposits H3K14 acetylation at the RAC2 promoter to activate RAC2 transcription. RAC2‐GTP subsequently promotes PAK1/2/3 phosphorylation, increasing tricarboxylic acid cycle flux and mitochondrial respiration to support glioblastoma malignancy.
Jilong Liu +13 more
wiley +1 more source

