Results 111 to 120 of about 4,143,379 (303)
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
Lifelong science learning [PDF]
, 2010 The author discusses the incorporation of lifelong learning in the study of science in New Zealand. He explains two preliminary thoughts related to the creation of a setting for lifelong learning in the field of science including the sustained enrichment
Barker, Miles
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Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
FEBS Open Bio, EarlyView.Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
Diverse Galaxies Lithograph [PDF]
, 2007 This Hubble Space Telescope image shows the diversity of galaxies in the universe. A huge elliptical galaxy, designated ESO 325-G004, dominates the image.
core
FEBS Open Bio, EarlyView.We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Surviving graduate school: Scientific communication
, 2020 This talk is about communicating research in a narrative format. It presents some research that supports the use of narrative as well as describes how the detective/mystery story design can be an effective way to organize scientific research presentations. This presentation was given at Vanderbilt University on 02/10/2020 from 12:10-1:00pm.
Borycz, Joshua, Carroll, Alexander J
openaire +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Historiographical thoughts in connection with the anniversary of Vladimir Fedorovich Gening
Поволжская археология, 2014 In connection with the 90 years’ anniversary of Vladimir Fyodorovich Gening (1924 – 1993), an eminent Soviet archaeologist, the milestones of the scholar’s biography and the principal directions of his research activity are traced in the article. A brief
Melnikova Olga M.
doaj