Results 31 to 40 of about 2,491,505 (285)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Le texte et l’image dans la formulation de la preuve en physique des matériaux

open access: yesRevue d'anthropologie des connaissances, 2011
The paper aims to determine the respective role of images and text in the elaboration of the proof in a scientific article published in Physical Review B in 2001.
Catherine Allamel-Raffin
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Плотность научного текста u подходы к ее изучению

open access: yesStylistyka, 2021
The article deals w ith one of the major properties of scientific discourse - density of content which is regarded as a text category. To study this category different approaches can be used: interdisciplinary,diachronic and synchronie (intertextual and
МАРИЯ П. KOTЮPOBA
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

OpenMinTeD: A Platform Facilitating Text Mining of Scholarly Content [PDF]

open access: yes, 2018
The OpenMinTeD platform aims to bring full text Open Access scholarly content from a wide range of providers together with Text and Data Mining (TDM) tools from various Natural Language Processing frameworks and TDM developers in an integrated ...
Anastasiou, Lucas   +12 more
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

The Use of Critical Reading in Understanding Scientific Texts on Academic Performance and Problem-solving Skills

open access: yesScience Education International, 2020
This study aimed to investigate the effect of critical reading (CR) practices in science courses on academic achievement, science performance level, and problem-solving skills. The experimental method and factorial design were used.
Özlem Koray , Sercan Çetinkılıç
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Do the students check the internal consistency of scientific texts or do they keep the first information they read? [PDF]

open access: yesInvestigações em Ensino de Ciências, 2003
This paper descrie the prepatarion and application of an instrument designed to assess the strategies students use to control comprehension when they read a short scientific text. It was applied to two groups of students from different school levels.
Carla I. Maturano   +2 more
doaj  

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