Results 91 to 100 of about 11,161,585 (334)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Scientific Theory and Teacher Education Theory

open access: yesAustralian Journal of Teacher Education, 1983
According to the empiricist tradition, science starts with observation. The observer should in an unprejudiced fashion faithfully record what he sees, hears, etc., about him. From his (admittedly) limited number of observation statements, the laws and theories of science can be established by generalization.
openaire   +3 more sources

D-region Probe Theory and Experiment Scientific Report No. 285 [PDF]

open access: yes
Weak shock effects and chemistry of lower D region, and blunt supersonic probe theory and first order ...
Kuo, T.-J.
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Racism and Aids: African Origin Theories of HIV-1 [PDF]

open access: yes, 1994
The AIDS epidemic, first discovered in the United States in 1981, has caused a great deal of speculation with regard to the origins of both the HIV-1 retrovirus and the early pathways for the epidemic itself. The African origins theory is the most widely
Hunt, Charles W.
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Le Corbusier

open access: yesПроект Байкал, 2019
Charles Edouard Jeanneret who changed his name to the symbolic Le Corbusier was the author of a hundred of buildings, dozens of books and articles, a symbol of the age and the culture and an iconic man.
Alexander Rappaport
doaj   +2 more sources

Scientific Realism without Rigid Designation in Kant's Analogies [PDF]

open access: yes, 2016
In Kant, Science, and Human Nature, Robert Hanna argues against a version of scientific realism founded on the Kripke/Putnam theory of reference, and defends a Kant-inspired manifest realism in its place. I reject Kriple/Putnam for different reasons than
Landy, David
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Scientific Realism without the Wave-Function: An Example of Naturalized Quantum Metaphysics [PDF]

open access: yes, 2019
Scientific realism is the view that our best scientific theories can be regarded as (approximately) true. This is connected with the view that science, physics in particular, and metaphysics could (and should) inform one another: on the one hand, science
Allori, Valia
core   +1 more source

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