Results 131 to 140 of about 11,161,585 (334)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
A Study of E-C Translation of Scientific and Technical Texts Fromthe Perspective of Functional Equivalence Theory [PDF]
ZANG Luying, Wang Chen
openalex +1 more source
Should the Equilibrium Point Hypothesis (EPH) be Considered a Scientific Theory?
Motor Control, 2015 R. Sainburg
semanticscholar +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Irkutsk as a Growth Point of Freedom
Проект Байкал, 2019 Active intellectual work is done in the field of architecture in Irkutsk: Vladimir Pavlov, probably the most prominent master of Soviet Modernism, realized his projects here; his apprentices work here; and Project Baikal journal is also published here ...
Alexander Rappaport
doaj +2 more sources
To explore the pathogenesis and scientific connotation of non‐alcoholic fatty liver based on the theory of turbid toxin of traditional Chinese medicine [PDF]
Guanjun Kou +6 more
openalex +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Thoughts about the Avant-Garde
Проект Байкал, 2019 The coming 100th anniversary of Bauhaus and VKhUTEMAS brings us back to the meaning of those cultural-historical professional events. Starting from boundless admiration and equally boundless abuse of avant-garde, we are now coming to its semantic basis ...
Alexander Rappaport
doaj +2 more sources