Results 41 to 50 of about 3,241,776 (340)
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
“Environmental movement” in architecture and related areas
Проект Байкал, 2021 The concept of “environmental approach” in the theory of architecture, urban planning and design is usually used in the singular, but its content is often interpreted in different ways.
Константин Кияненко
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FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
Special Relativity: Scientific or Philosophical Theory?
, 2016 In this article, we argue that the theory of special relativity, as formulated by Einstein, is a philosophical rather than a scientific theory. What is scientific and experimentally supported is the formalism of the relativistic mechanics embedded in the
Sochi, Taha
core +2 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
A New Age of Theater Architecture
Проект Байкал, 2020 The article considers the reasons of the change in the form-making principles in architecture of entertainment facilities of the late 20th – early 21st centuries: the change in social conditions, development of stage technologies; improvement of ...
Alexander Anisimov
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FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
Piękno jako przykład pozaempirycznego kryterium wyboru teorii naukowej
Zagadnienia Filozoficzne w Nauce, 2010 It is sometimes argued that beauty and science have nothing in common. This is not necessarily true. When speaking of beauty in science we are touching two branches of knowledge: aesthetics and physics.
Diana Ciszewska, Marek Szydłowski
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FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source