Results 91 to 100 of about 132,694 (348)

Numerical evaluation of spray position for improved nasal drug delivery [PDF]

open access: yesarXiv, 2019
Topical intra-nasal sprays are amongst the most commonly prescribed therapeutic options for sinonasal diseases in humans. However, inconsistency and ambiguity in instructions show a lack of definitive knowledge on best spray use techniques. In this study, we have identified a new usage strategy for nasal sprays available over-the-counter, that ...
arxiv  

Advancing diagnostics and therapy in transthyretin amyloid cardiomyopathy

open access: yes
ESC Heart Failure, EarlyView.
Katarzyna Holcman, Michał Tkaczyszyn
wiley   +1 more source

Thermo‐Responsive Polymer‐Based Nanoparticles: From Chemical Design to Advanced Applications

open access: yesMacromolecular Rapid Communications, EarlyView.
This work explores the chemical design and applications of thermo‐responsive polymer‐based nanoparticles. Focusing on PNIPAM and POEGMA block copolymers, it highlights their thermo‐responsive behaviors and advanced functionalities in imaging, drug delivery, and cell proliferation studies.
Giuseppe Nunziata   +4 more
wiley   +1 more source

Improving Lung Scintigraphy [PDF]

open access: yesJournal of Nuclear Medicine, 2009
1919 Objectives Investigate the feasibility of D- and L-enantiomers of [18F]-labelled 2- and 6-FDOPA for melanoma imaging. Methods D- and L-enantiomers of [18F]2- and 6-FDOPA were prepared by the direct fluorination of DOPA. 20 mBq of each tracer (0.2 mL) was injected into the tail veins of mice bearing B16-F10 mealnoma tumor after they were ...
openaire   +3 more sources

Being Prodromal: Current Criteria in the Context of Isolated REM Sleep Behavior Disorder

open access: yesMovement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Isolated REM sleep behavior disorder (iRBD) indicates an early α‐synucleinopathy with approximately 90% of individuals pheno‐converting to Parkinson's disease (PD), dementia with Lewy bodies (DLB), or multiple system atrophy (MSA). Recently, prodromal disease definitions (pPD, pDLB, pMSA) have been introduced.
Anja Ophey   +5 more
wiley   +1 more source

Hybrid SPECT-CT for characterizing isolated vertebral lesions observed by bone scintigraphy: comparison with planar scintigraphy, SPECT, and CT.

open access: yesDiagnostic and Interventional Radiology, 2013
PURPOSE We aimed to assess the role of single photon emission computed tomography-computed tomography (SPECT-CT) for characterizing isolated vertebral lesions observed by bone scintigraphy compared to planar scintigraphy, SPECT, and CT, and to evaluate ...
P. Sharma   +6 more
semanticscholar   +1 more source

Salivary CXCL13 in relation to scintigraphy in early detection of secondary Sjogren’s syndrome

open access: yesEgyptian Rheumatology and Rehabilitation, 2018
Background Sjogren’s syndrome (SS) is a systemic autoimmune disease in which immune cells attack and destroy the exocrine glands. CXCL13 directs B-cell chemotaxis and is elevated in several autoimmune diseases.
Salwa G Moussa   +4 more
doaj   +1 more source

Genetic cardiomyopathy mimicking isolated cardiac sarcoidosis: Diagnostic challenges with positron emission tomography

open access: yes
ESC Heart Failure, EarlyView.
Daigo Nishijo   +19 more
wiley   +1 more source

Progranulin Mutation Manifesting as Parkinson Disease: A Case Series from the PADUA‐CESNE Cohort

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Mutations in progranulin (GRN) are associated with frontotemporal dementia, although a Parkinson disease (PD) phenotype is uncommon, especially in young patients. Cases We report three subjects from the PADUA‐CESNE cohort, meeting diagnostic criteria for PD, with onset under age 55.
Giulia Bonato   +8 more
wiley   +1 more source

Comparison of radiation exposure and cost between dynamic computed tomography and sestamibi scintigraphy for preoperative localization of parathyroid lesions.

open access: yesJAMA Surgery, 2013
IMPORTANCE Dynamic computed tomography (CT) is emerging as a first-line alternative to sestamibi scintigraphy for preoperative localization of parathyroid lesions.
C. Madorin   +10 more
semanticscholar   +1 more source

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