Results 181 to 190 of about 164,155 (331)

Design and Synthesis of Tetrahydropyrrolo[3,4‐c]Pyrazole Sigma‐1 Receptor Ligands

open access: yesChemMedChem, EarlyView.
This study highlights the tetrahydropyrrolo[3,4‐c]pyrazole scaffold as a promising platform for S1R ligands development. Key findings include compound 19’s high S1R affinity (Ki=75 nM), influenced by strategic nitrogen substitutions and reduced steric hindrance.
Giuseppe Cosentino   +7 more
wiley   +1 more source

First demonstration of a TES based cryogenic Li 2 MoO 4 detector for neutrinoless double beta decay search. [PDF]

open access: yesEur Phys J C Part Fields
Bratrud G   +24 more
europepmc   +1 more source

Rare‐Earth‐Based Nanomaterials for Cancer Therapy

open access: yesCancer Nexus, EarlyView.
This review highlights recent advances in cancer therapy using rare‐earth‐based nanomaterials (RENMs), covering applications such as fluorescent surgical tumor resection, light‐triggered therapy, enzyme‐catalyzed therapy, enhanced radiotherapy, and lanthanide‐coordinated nanoformulations.
Linshuo Gao   +3 more
wiley   +1 more source

A Direct Measurement of the Absolute Energies of Protonated Gly‐Pro‐Gly‐Gly Conformations Using Ion Mobility Spectrometry and Guided Ion Beam Tandem Mass Spectrometry

open access: yesChemPhysChem, EarlyView.
Relative energies of the cis and trans conformers of the protonated tetrapeptide, Gly‐Pro‐Gly‐Gly, selected by ion mobility spectrometry are measured using threshold collision‐induced dissociation. The trans conformation was found to be more stable than the cis conformation by 4.5 ± 2.5 kJ mol−1 at 0 K, a value in agreement with several levels of ...
Brandon C. Stevenson   +3 more
wiley   +1 more source

Additive manufacturing of a 3D-segmented plastic scintillator detector for tracking and calorimetry of elementary particles. [PDF]

open access: yesCommun Eng
Weber T   +15 more
europepmc   +1 more source

Conformation Dependent Room Temperature Phosphorescence in Organic Materials

open access: yesChemPhotoChem, EarlyView.
Room temperature phosphorescence from organic materials in the solid state can be tuned owing to changes in the molecular arrangement occurring in crystalline and amorphous phases. This review presents recent results that discuss conformation dependent triplet emission, revealing its role in the design of organic functional materials with diverse ...
Andrea Fermi
wiley   +1 more source

Simulation study for the energy and position reconstruction performances of the beam monitoring system of Carbon Ion Radiation Therapy using GEANT4. [PDF]

open access: yesPLoS One
Eo Y   +33 more
europepmc   +1 more source

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