Results 241 to 250 of about 164,436 (341)

3D imaging of neuronal inclusions and protein aggregates in human neurodegeneration by multiscale x‐ray phase‐contrast tomography

Brain Pathology, EarlyView.
x‐ray phase‐contrast tomography enabled three‐dimensional, label‐free visualization and quantification of protein aggregates in neurodegenerative diseases with isotropic submicrometer resolution. The study revealed distinct electron density patterns in Lewy bodies, Hirano bodies, granulovacuolar degeneration, and amyloid plaques, highlighting their ...
Jonas Franz, Jakob Reichmann, Marina Eckermann, Thea Würfel, Artur Groh, Syed Fatima Qadri, Katja Schulz, Brit Mollenhauer, Christine Stadelmann, Tim Salditt   +9 more
wiley   +1 more source

Protocol for fixation and staining of postmortem human brain tissue optimized for focused ion beam-scanning electron microscopy. [PDF]

STAR Protoc
Maier MJ, Lewis DA, Freyberg Z, Glausier JR.   +3 more
europepmc   +1 more source

A homogeneous scintillation proximity assay for acetyl coenzyme A carboxylase coupled to fatty acid synthase

, 2006
Ramakrishna Seethala, Zhengping Ma, Rajasree Golla, Dong Cheng   +3 more
openalex   +1 more source

Divergence in μ and δ opioid receptor pharmacology in neurons and antinociceptive efficacy in neuropathic pain: Insights from MP135 and CYM51010

British Journal of Pharmacology, EarlyView.
Background and purpose Opioids targeting the μ opioid receptor remain largely ineffective in neuropathic pain conditions, emphasizing the need for novel therapeutic strategies. MP135 was reported to reduce thermal nociception in naive animals by activating μ‐δ opioid receptor heteromers.
Perrine Inquimbert, Chantal Fitterer, Sylvain Hugel, Mila Jesic, Yannick Goumon, Virgine Andry, Severine Schneider, Francois Daubeuf, Abdelfattah Faouzi, Stephane Doridot, Susruta Majumdar, Frederic Bihel, Martine Schmitt, Dominique Massotte   +13 more
wiley   +1 more source

A theory of scintillation for two‐component power law irregularity spectra: Overview and numerical results

, 2016
C. Carrano, C. Rino
semanticscholar   +1 more source

Design and characterization of a novel scintillator array for UHDR PBS proton therapy surface dosimetry. [PDF]

Med Phys
Vasyltsiv R, Harms J, Clark M, Gladstone DJ, Pogue BW, Zhang R, Bruza P.   +6 more
europepmc   +1 more source

Vesicular glutamate transporter VGLUT2 expression emerges in substantia nigra dopamine neurons in mouse models of parkinsonism in the absence of neurodegeneration

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Subsets of midbrain dopamine (DA) neurons express the vesicular glutamate transporter VGLUT2 and can release the excitatory neurotransmitter glutamate. VGLUT2+ DA neurons of the substantia nigra pars compacta (SNc) were shown to be more resistant to neurodegeneration in animal models of Parkinson's disease (PD ...
Sivakumar Srinivasan, Christian Pifl, Thomas Steinkellner   +2 more
wiley   +1 more source

Protocol to measure endogenous GlcNAc-1-phosphotransferase activity in SK-MEL-30 cells. [PDF]

STAR Protoc
Doray B, Henn D, Yang X, Li M, Dickson P.   +4 more
europepmc   +1 more source

Light yield measurement of the Ce3+ activated LuAG nano-powder garnet scintillating detector

Hamza Mekki, L. Guerbous, Hicham Bousbia-Salah, Billel Zahra, A. Boukerika   +4 more
openalex   +2 more sources

Neutron-Gamma Pulse Shape Discrimination with a NE-213 Liquid Scintillator by Using Digital Signal Processing Combined with Similarity Method

, 2012
Mardiyanto Mardiyanto
openalex   +2 more sources