Results 231 to 240 of about 679,715 (383)

Deciphering the Immunomodulatory Function of GSN+ Inflammatory Cancer‐Associated Fibroblasts in Renal Cell Carcinoma Immunotherapy: Insights From Pan‐Cancer Single‐Cell Landscape and Spatial Transcriptomics Analysis

Cell Proliferation, EarlyView.
Pan‐cancer scRNA‐seq and ST‐seq analyses identify GSN+ inflammatory cancer‐associated fibroblasts (CAFs) and their spatial distribution in immune checkpoint inhibitor (ICI) therapy. The Caf.Sig model accurately predicts ICI response across cancers using CAF gene signatures and machine learning.
Shan Li, Xinwei Zhou, Haoqian Feng, Kangbo Huang, Minyu Chen, Mingjie Lin, Hansen Lin, Zebing Deng, Yuhang Chen, Wuyuan Liao, Zhengkun Zhang, Jinwei Chen, Bohong Guan, Tian Su, Zihao Feng, Guannan Shu, Anze Yu, Yihui Pan, Liangmin Fu   +18 more
wiley   +1 more source

Detection and measurement of radioactive substances in water and food: a narrative review. [PDF]

Ital J Food Saf
Touranlou FA, Moghimani M, Marhamati M, Rezaie M.   +3 more
europepmc   +1 more source

Development of the alcohol‐free and low‐alcohol drinks market in Great Britain from 2011 to 2022: Narrative timelines based on a documentary review of off‐trade retail magazines and market intelligence reports

Drug and Alcohol Review, EarlyView.
Abstract Issue There is a growing alcohol‐free and low‐alcohol (no/lo) drinks market in Great Britain. Insight about when this emerged and how it has developed is needed to inform and interpret the growing body of research into the use of no/lo drinks. We therefore document the development of the no/lo market in Great Britain between 2011 and 2022 and ...
Nathan Critchlow, Amber Morgan, Kathryn Angus, Rebecca Howell, Niamh Fitzgerald, Inge Kersbergen, John Holmes   +6 more
wiley   +1 more source

Quantitative Measurement of the Kinase Activity of Wildtype ALPK1 and Disease-Causing ALPK1 Mutants Using Cell-Free Radiometric Phosphorylation Assays. [PDF]

Bio Protoc
Snelling T.
europepmc   +1 more source

PI5P4K inhibitors: promising opportunities and challenges

The FEBS Journal, EarlyView.
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi, Lisa Nagase, Shun Kageyama, Hirotaka Kanoh, Masashi Oshima, Aki Ogawa‐Iio, Yoshiki Ikeda, Yuki Fujii, Sei Kondo, Natsuki Osaka, Takeshi Masuda, Tsukasa Ishihara, Yoshikazu Nakamura, Yoshihisa Hirota, Takehiko Sasaki, Toshiya Senda, Atsuo T. Sasaki   +16 more
wiley   +1 more source

Gαs‐specific structural elements attenuate interactions with regulator of G protein signaling (RGS) proteins

The FEBS Journal, EarlyView.
Heterotrimeric (αβγ) G proteins are usually inactivated by regulators of G protein signaling (RGS) proteins, but Gαs is an exception. Comparative structural analysis identified unique Gαs structural elements that may interfere with RGS binding. Mutagenesis and biochemical assays showed that three residues in the Gαs GTPase domain are both necessary and
Sabreen Higazy‐Mreih, Meirav Avital‐Shacham, Christian LeGouill, Michel Bouvier, Mickey Kosloff   +4 more
wiley   +1 more source

Comparison of treatment‐emergent resistance‐associated mutations and discontinuation due to adverse events among integrase strand transfer inhibitor‐based single‐tablet regimens and cabotegravir + rilpivirine for the treatment of virologically suppressed people with HIV: A systematic literature review and network meta‐analysis

HIV Medicine, EarlyView.
Abstract Objective This study evaluated rates of treatment‐emergent resistance‐associated mutations (TE‐RAMs) and discontinuation due to adverse events (DC‐AEs) across integrase strand transfer inhibitor (INSTI)‐based single‐tablet regimens and injectable cabotegravir + rilpivirine (CAB + RPV) in virologically suppressed people with HIV.
Ishfaq Rashid, Nathan R. Unger, Connor Willis, Teerapon Dhippayom, Moti Ramgopal, Elizabeth M. Sherman, Nicholas Yared, Rachel Safran, Edwin Swiatlo, Amy R. Weinberg, Soodi Navadeh, Howard Weston Schmutz, Nathorn Chaiyakunapruk   +12 more
wiley   +1 more source

Development of local-power-free, remote α-particle detection using optical fibers. [PDF]

J Radiat Res
Pfeifer KB, Weber TM, Martin JE.
europepmc   +1 more source

Determination of Radon Concentration in Water Using Liquid Scintillation Counter

, 2004
Yumi Yasuoka, Tadashi ISHII, Yasuhide Kataoka, Tsuyoshi KUBO, Hirofumi Suda, Shinji Tokonami, Tetsuo Ishikawa, Masaki Shinogi   +7 more
openalex   +2 more sources

Recovery and protection of photo‐damaged hairs with keratin‐encapsulated cationic liposomes

International Journal of Cosmetic Science, EarlyView.
Homogeneous and highly stable cationic liposomes encapsulated with keratin were fabricated using the high‐pressure homogenization method, which could improve the adherence of keratin on the hair cuticle and its penetration into hair fibres, thereby effectively enhancing the recovery of photo‐damaged hair.
Hoai‐Thuong Duc Bui, Su Ji Kim, Jihui Jang, Jun Bae Lee, Hyuk Sang Yoo   +4 more
wiley   +1 more source