Results 231 to 240 of about 75,321 (301)

Disease Aggravation With Age in an Experimental Model of Multiple Sclerosis: Role of Immunosenescence

open access: yesAging Cell, EarlyView.
Age‐related differences in EAE outcomes stem from combined peripheral and CNS factors. Key peripheral adaptive immunity changes include altered naïve/memory T cell ratios, Th1 skewing, increased suppressive Tregs, CD4+ T cell exhaustion, enhanced B cell antigen presentation, and reduced NK cell cytotoxicity.
María Dema   +6 more
wiley   +1 more source

Imatinib decreases germ cell survival and germline stem cell proliferation in rodent testis ex vivo and in vitro

open access: yesAndrology, EarlyView.
Abstract Background Imatinib and dasatinib are tyrosine kinase inhibitors (TKIs) increasingly used to treat several diseases in both children and adults at fertile age. We have previously shown that imatinib has adverse effects on developing testis, and imatinib‐treated male patients have been reported to have reduced sperm counts.
Anna Eggert   +10 more
wiley   +1 more source

Advancements in radiocarbon dating: An overview of its impact on Mexican archaeology

open access: yesArchaeometry, EarlyView.
Abstract In this article, we provide a concise historical summary tracing the evolution of radiocarbon dating techniques in Mexico and Central America. We explore the contributions of early pioneers who first employed radiocarbon dating methods, leading to the establishment of a Mexican accelerator mass spectrometry laboratory. The study highlights its
Corina Solís   +3 more
wiley   +1 more source

Ligand bias and inverse agonism on 5‐HT2A receptor‐mediated modulation of G protein activity in post‐mortem human brain

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Whereas biased agonism on the 5‐HT2A receptor has been ascribed to hallucinogenic properties of psychedelics, no information about biased inverse agonism on this receptor is available. In schizophrenia, increased 5‐HT2A receptor constitutive activity has been suggested, highlighting the therapeutic relevance of inverse ...
Itziar Muneta‐Arrate   +4 more
wiley   +1 more source

Children's Evaluations of Empathizers

open access: yesChild Development, EarlyView.
ABSTRACT Children's evaluations of empathizers were examined using vignette‐based tasks (N = 159 4‐ to 7‐year‐old U.S. children, 82 girls, 52% White) between March 2023 and March 2024. Children typically evaluated empathizers positively compared to less empathic others.
Alexis S. Smith‐Flores   +2 more
wiley   +1 more source

Determination of Radon Concentration in Water Using Liquid Scintillation Counter

open access: bronze, 2004
Yumi Yasuoka   +7 more
openalex   +2 more sources

‘It can be an abuse, even though both have consented’: Swedish preschool practitioners' discussions about teaching (sexual) consent to preschoolers

open access: yesChildren &Society, EarlyView.
Abstract This article describes how (sexual) consent is constructed as an objective for teaching in Swedish preschool. An age‐critical analysis of focus‐group discussions with preschool practitioners shows how a didactic of consent is constructed and characterised: (1) The child should be trained to feel non‐ambivalence.
Magdalena Hulth
wiley   +1 more source

‘I like to dance with the flowers!’: Exploring the possibilities for biodiverse futures in an urban forest school

open access: yesChildren &Society, EarlyView.
Abstract This article explores the ways in which ‘forest school’, an educational approach where children engage in creative and play based activities in a ‘natural’ environment, can contribute towards Sustainable Development Goal 15 (SDG 15) by promoting sustainable use of terrestrial ecosystems and by helping address biodiversity loss. Drawing on data
Hannah Hogarth
wiley   +1 more source

Development of the alcohol‐free and low‐alcohol drinks market in Great Britain from 2011 to 2022: Narrative timelines based on a documentary review of off‐trade retail magazines and market intelligence reports

open access: yesDrug and Alcohol Review, EarlyView.
Abstract Issue There is a growing alcohol‐free and low‐alcohol (no/lo) drinks market in Great Britain. Insight about when this emerged and how it has developed is needed to inform and interpret the growing body of research into the use of no/lo drinks. We therefore document the development of the no/lo market in Great Britain between 2011 and 2022 and ...
Nathan Critchlow   +6 more
wiley   +1 more source

Predicting voluntary contributions by “revealed‐preference Nash‐equilibrium”

open access: yesEconomic Inquiry, EarlyView.
Abstract One‐shot public‐good situations are prominent in the public debate, and a prime example for behavior diverging from the standard Nash‐equilibrium. Could a Nash‐equilibrium predict one‐shot public‐good behavior in principle? A “revealed‐preference Nash‐equilibrium” (rpne) out‐of‐sample predicts behavior, outperforming other social‐preference ...
Irenaeus Wolff
wiley   +1 more source

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