Results 181 to 190 of about 1,458,589 (326)

Design of Experiments (DoE)‐Optimized Polymeric Oxytocin Nanoparticles for Enhanced Nose‐to‐Brain Delivery

open access: yesSmall, Volume 22, Issue 8, 6 February 2026.
Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad   +11 more
wiley   +1 more source

Recent Advances in Metal‐Organic Framework‐Integrated Nanocomposite Hydrogels for Sensors and Sensing Systems

open access: yesSmartMat, Volume 7, Issue 1, February 2026.
Metal‐organic framework–hydrogel composites are explored as multifunctional materials for next‐generation sensors and sensing systems. This review summarizes recent advances in employing these smart composites to fabricate optical, electrochemical, and electromechanical sensors, emphasizing their potential in healthcare, biomedical diagnostics ...
Md Sazzadur Rahman   +2 more
wiley   +1 more source

High‐Precision Prediction of Auroral Substorm Expansion Phase Evolution Using a Spatio‐Temporal Attention Deep Learning Model

open access: yesSpace Weather, Volume 24, Issue 2, February 2026.
Abstract Auroral substorms are a key manifestation of solar‐terrestrial interactions and the release of energy within the Earth's magnetosphere. The expansion phase, which is characterized by rapid changes in auroral morphology and intensity, poses significant space weather risks to satellite operations and communication systems.
Qiuju Yang   +3 more
wiley   +1 more source

Evolution of crystallographic texture and material anisotropy effects resulting from uniaxial deformation for high‐strength steels with high manganese content

open access: yesJournal of Applied Crystallography, Volume 59, Issue 1, Page 163-178, February 2026.
The present study investigates the deformation behavior of high‐strength steels and the associated evolution of material anisotropy. Particular focus is placed on the impact of crystallographic texture and intergranular strains on how residual stresses can be evaluated using X‐ray diffraction and the associated assessment of weld seams in the ...
Michael Zuern   +3 more
wiley   +1 more source

Estimation of contrast agents using a 2-dimensional photon counting CT detector combined with MPPC and YGAG scintillator array

open access: hybrid
F. Lucyana   +12 more
openalex   +1 more source

Assembly and Functional Coordination of Two Families of Metabolic Organelles in Salmonella

open access: yesMicrobial Biotechnology, Volume 19, Issue 2, February 2026.
Engineered Salmonella enterica co‐expressing native metabolosomes and synthetic carboxysomes formed hybrid bacterial microcompartments (BMCs) through shell protein exchange while maintaining cargo segregation, revealing the principles of BMC coexistence and modular assembly.
Ping Chang   +5 more
wiley   +1 more source

Oesophageal Epithelial Cell‐Intrinsic MHCII Regulates Food Antigen‐Dependent Eosinophilic Esophagitis in an IFNγ‐Dependent Manner

open access: yesClinical &Experimental Allergy, Volume 56, Issue 2, Page 124-136, February 2026.
We found that oesophageal epithelial cells upregulate MHCII expression during active EoE in humans and a mouse model. MHCII expression by EECs was governed by IFNγ‐inducible transcriptional elements. EEC‐intrinsic MHCII promoted regulatory T cell accumulation and attenuated eosinophilic oesophageal inflammation.
Eric M. Rodríguez‐López   +12 more
wiley   +1 more source

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