Results 241 to 250 of about 22,137 (302)

Agonist‐specific conformational dynamics at the β2‐adrenoceptor dictate allosteric modulation of Gαs signalling and bronchodilation

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose β2‐adrenoceptor (β2AR) agonists are the cornerstone of asthma therapy and promote bronchodilation through Gαs signalling in airway smooth muscle (ASM), but their efficacy is limited by β‐arrestin‐mediated β2AR desensitization.
Sushrut D. Shah, Joshua Richard, Suvankar Ghosh, Jillian Jerwick, Joice T. Gavali, Raymond B. Penn, Alexander D. MacKerell Jr, Deepak A. Deshpande   +7 more
wiley   +1 more source

A journey to ITACA: Ion Tracking with Ammonium Cations Apparatus. [PDF]

Eur Phys J C Part Fields
Gómez-Cadenas JJ, Arazi L, Elorza M, Freixa Z, Monrabal F, Pazos A, Renner J, Soleti SR, Torelli S.   +8 more
europepmc   +1 more source

Transient Hyperparathyroidism and Severe Intrauterine Osteopenia Linked to Novel Homozygous TRPV6 Deletion

Clinical Endocrinology, EarlyView.
ABSTRACT Context Placental calcium (Ca2+) transport is essential for foetal bone mineralisation and development, as well as for Ca2+ homoeostasis. Rare mutations in transient receptor potential vanilloid (TRPV) 6 of the infant cause insufficient maternal‐foetal Ca2+ transport through the placenta.
Teodora Grigore, Quinty Leusink, Femke Latta, Bram van der Eerden, Paul de Laat, Danielle van der Kaay, Joost Hoenderop   +6 more
wiley   +1 more source

Investigating the timing behavior of compton scattering in BGO for time-of-flight PET. [PDF]

Phys Med Biol
Yi M, Lee D, Gola A, Merzi S, Penna M, Cherry SR, Lee JS, Kwon SI.   +7 more
europepmc   +1 more source

‘I like to dance with the flowers!’: Exploring the possibilities for biodiverse futures in an urban forest school

Children &Society, EarlyView.
Abstract This article explores the ways in which ‘forest school’, an educational approach where children engage in creative and play based activities in a ‘natural’ environment, can contribute towards Sustainable Development Goal 15 (SDG 15) by promoting sustainable use of terrestrial ecosystems and by helping address biodiversity loss. Drawing on data
Hannah Hogarth
wiley   +1 more source

The Place for Form in Wollheim's Lectures on Formalism and Pictorial Organization

European Journal of Philosophy, EarlyView.
Abstract At the time of his death, Richard Wollheim was writing a short book on Formalism and Pictorial Organization. Much of it, but by no means all of it, had been published before (it has come out posthumously in its entirety in late 2025). Here I do two things. First, I have provided a rather detailed exegesis concentrating on the parts of the book
Gary Kemp
wiley   +1 more source

Towards Real-Time Aquatic Monitoring of Strontium-90: Performance Evaluation of CaF₂(Eu) and ZnSe(Al,O) Scintillators. [PDF]

Sensors (Basel)
Kolnikaj A, Gamage KAA, Popoola O, Graham J, Di Buono A.   +4 more
europepmc   +1 more source

Novel directional detector for radioactive material search and monitoring. [PDF]

Sci Rep
Peräjärvi K, Bogdanoff V.
europepmc   +1 more source

Penetration enhancement effects of topically applied crosslinked hyaluronic acid

International Journal of Cosmetic Science, EarlyView.
Cross‐linked hyaluronic acid (HA) was demonstrated to enhance the topical delivery of a variety of hydrophilic actives into the skin. This phenomenon was observed for both small molecules and macromolecules, the latter of which was analysed with MALDI mass spectrometry imaging (MALDI‐MSI).
Aaron Cohen, Raphael Legouffe, Krystal House, Paul Duhamel, Aurore Tomezyk, Mathieu Gaudin, Junhong Mao, David Bonnel   +7 more
wiley   +1 more source

High-Speed Detection of X-ray Pulses Using a Digital Counter Coupled with Perovskite Composite Scintillators. [PDF]

ACS Appl Mater Interfaces
Khaliq S, Faleiros MC, Zhang L, Hasanov BE, de Oliveira Filho JI, Bayindir M, Bakr OM, Salama KN, Mohammed OF.   +8 more
europepmc   +1 more source