Results 161 to 170 of about 47,910 (271)

Becoming monstrous: Beauty norms, body image, and discursive limits on compassion in The Substance

open access: yesNutrition &Dietetics, EarlyView.
Abstract Aim This study analyses the Hollywood body horror film The Substance to explore how Western beauty culture regulates emotions and bodies. It aims to explore compassion within dominant body image discourses and considers how this impacts dietetic care. Methods Using Foucauldian discourse analysis informed by affect theory, the film was analysed
Phillip Joy
wiley   +1 more source

Ultrasound, PET/CT or temporal artery biopsy for giant cell arteritis? A prospective diagnostic accuracy study (the GAME‐study)

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To investigate the diagnostic performance of ultrasound, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose positron emission tomography/computed tomography (2‐[18F]FDG PET/CT) and temporal artery biopsy (TAB) in giant cell arteritis (GCA). Methods This was a prospective single‐centre diagnostic accuracy study (ClinicalTrials.gov NCT05248906).
Michael S. Hansen   +10 more
wiley   +1 more source

A Multi‐Analytical Approach for the Compositional Characterization and Chronological Discrimination of Benin (Nigeria) Metal Sculptures

open access: yesArchaeometry, EarlyView.
ABSTRACT This study presents a multi‐analytical archaeometric approach for the compositional characterization and chronological discrimination of Benin metal sculptures in relation to the 1897 Punitive Expedition. The methodology integrates elemental composition (XRF and ICP), stable lead isotope ratios (MC‐ICP‐MS) for alloy system characterization ...
I. Torraba   +5 more
wiley   +1 more source

Divergence in μ and δ opioid receptor pharmacology in neurons and antinociceptive efficacy in neuropathic pain: Insights from MP135 and CYM51010

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and purpose Opioids targeting the μ opioid receptor remain largely ineffective in neuropathic pain conditions, emphasizing the need for novel therapeutic strategies. MP135 was reported to reduce thermal nociception in naive animals by activating μ‐δ opioid receptor heteromers.
Perrine Inquimbert   +13 more
wiley   +1 more source

Vesicular glutamate transporter VGLUT2 expression emerges in substantia nigra dopamine neurons in mouse models of parkinsonism in the absence of neurodegeneration

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Subsets of midbrain dopamine (DA) neurons express the vesicular glutamate transporter VGLUT2 and can release the excitatory neurotransmitter glutamate. VGLUT2+ DA neurons of the substantia nigra pars compacta (SNc) were shown to be more resistant to neurodegeneration in animal models of Parkinson's disease (PD ...
Sivakumar Srinivasan   +2 more
wiley   +1 more source

A PK/PD study on antihyperalgesia by an α2/3‐GABAA receptor PAM in mice: Lack of tolerance liability and potential involvement of γ1‐GABAA receptors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose GABAA receptors (GABAARs) are heteropentameric ion channels that control almost all CNS functions, including spinal nociception. Most GABAARs contain a γ2 subunit but differ in their α and β subunit composition. TPA023B is an α2/α3 subtype selective, non‐sedative, positive allosteric modulator (PAM) with antihyperalgesic
Elena Neumann   +12 more
wiley   +1 more source

‘I like to dance with the flowers!’: Exploring the possibilities for biodiverse futures in an urban forest school

open access: yesChildren &Society, EarlyView.
Abstract This article explores the ways in which ‘forest school’, an educational approach where children engage in creative and play based activities in a ‘natural’ environment, can contribute towards Sustainable Development Goal 15 (SDG 15) by promoting sustainable use of terrestrial ecosystems and by helping address biodiversity loss. Drawing on data
Hannah Hogarth
wiley   +1 more source

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