Results 191 to 200 of about 51,769 (308)

A PK/PD study on antihyperalgesia by an α2/3‐GABAA receptor PAM in mice: Lack of tolerance liability and potential involvement of γ1‐GABAA receptors

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose GABAA receptors (GABAARs) are heteropentameric ion channels that control almost all CNS functions, including spinal nociception. Most GABAARs contain a γ2 subunit but differ in their α and β subunit composition. TPA023B is an α2/α3 subtype selective, non‐sedative, positive allosteric modulator (PAM) with antihyperalgesic
Elena Neumann, Mariana O. Popa, Karen T. Elvers, Misa Oyama, Daniel Ulrich, Marcus Hanley, Gui Jie Feng, Thomas Hathaway, William T. Ralvenius, Thomas Grampp, Dietmar Benke, John R. Atack, Hanns Ulrich Zeilhofer   +12 more
wiley   +1 more source

Toward Noninvasively Imaging pH at the Surface of Implanted Orthopedic Devices in Live Rabbits Using X-ray Excited Luminescence Chemical Imaging. [PDF]

Adv Healthc Mater
Uzair U, Wang F, Benza D, Raval YS, Bhattacharya S, Tzeng TJ, Anker JN.   +6 more
europepmc   +1 more source

Performance stabilization of scintillation spectrometers for aerosol monitoring

, 2019
Feliks Finkel, Igors Krainukovs, Vasily Litvinsky, V. Gostilo   +3 more
openalex   +2 more sources

Oesophageal Epithelial Cell‐Intrinsic MHCII Regulates Food Antigen‐Dependent Eosinophilic Esophagitis in an IFNγ‐Dependent Manner

Clinical &Experimental Allergy, EarlyView.
We found that oesophageal epithelial cells upregulate MHCII expression during active EoE in humans and a mouse model. MHCII expression by EECs was governed by IFNγ‐inducible transcriptional elements. EEC‐intrinsic MHCII promoted regulatory T cell accumulation and attenuated eosinophilic oesophageal inflammation.
Eric M. Rodríguez‐López, Rachel L. Clement, Megha Lal, Yusen Zhou, Stephen D. Carro, Charles‐Antoine Assenmacher, Ravi Gautam, Jarad Beers, Amanda B. Muir, Jonathan M. Spergel, Melanie A. Ruffner, Laurence C. Eisenlohr, David A. Hill   +12 more
wiley   +1 more source

The Scintillation Spectrometer and its Application in Nuclear Time-Correlation Studies.

, 1952
Kenneth Irwin Roulstan
openalex   +1 more source

Facilitated Transport of Organic Contaminants in a High Concentration, Multicomponent Plume

Groundwater Monitoring &Remediation, EarlyView.
Abstract A field experiment evaluated the transport of organic contaminants in a plume from hazardous waste disposal areas at the Rocky Mountain Arsenal. The plume contained many xenobiotic contaminants, with widely varying expected mobilities.
D. M. Mackay, B. Myller, G. C. Bianchi‐Mosquera, B. D. Honeyman, M. Schirmer, R. M. Allen‐King, W. P. Ball, R. L. Stollar   +7 more
wiley   +1 more source

A novel approach for proton therapy pencil beam scanning patient specific quality assurance using an integrated detector system and 3D dose reconstruction. [PDF]

Front Oncol
Bateman JJ, Escribano-Rodriguez S, Flynn S, Price T, Radogna R, Shaikh S, Barnett H, Godden C, Warren M, Febian, Burne C, Warry A, Harrison-Carey L, Baker C, Jolly S.   +14 more
europepmc   +1 more source

Fine-grained hodoscopes based on scintillating optical fibers

, 1985
S. Borenstein, R. C. Strand
openalex   +2 more sources

Evidence for increased background neural noise in migraine with aura: Hyperactive but not hyperresponsive

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study had two aims: (1) to investigate the contrast gain in migraine and compare it to that in photosensitive epilepsy; (2) to explore any effects of colored spectacles (precision ophthalmic tints [POT]) on contrast gain. Background Individuals with migraine with aura (MA) typically show high amplitude electrophysiological ...
Louise O'Hare, Paul B. Hibbard, Arnold J. Wilkins   +2 more
wiley   +1 more source

Regulating through-space charge transfer interactions in donor-acceptor MOFs for thermally activated delayed fluorescence and X-ray scintillators. [PDF]

Chem Sci
Yan X, Song SY, Liang S, Liu KK, Liu XT, Lu C.   +5 more
europepmc   +1 more source