Results 221 to 230 of about 215,881 (371)
The plastic scintillator detector for DAMPE [PDF]
Yu-hong Yu +24 more
semanticscholar +1 more source
Background and purpose Opioids targeting the μ opioid receptor remain largely ineffective in neuropathic pain conditions, emphasizing the need for novel therapeutic strategies. MP135 was reported to reduce thermal nociception in naive animals by activating μ‐δ opioid receptor heteromers.
Perrine Inquimbert +13 more
wiley +1 more source
Single-shot X-ray and near-infrared (NIR) dual-mode fusion imaging based on bifunctional NIR scintillators. [PDF]
Ran P +8 more
europepmc +1 more source
Abstract Background and Purpose Subsets of midbrain dopamine (DA) neurons express the vesicular glutamate transporter VGLUT2 and can release the excitatory neurotransmitter glutamate. VGLUT2+ DA neurons of the substantia nigra pars compacta (SNc) were shown to be more resistant to neurodegeneration in animal models of Parkinson's disease (PD ...
Sivakumar Srinivasan +2 more
wiley +1 more source
In Situ Dose Measurements in Brachytherapy Using Scintillation Detectors Based on the Al<sub>2</sub>O<sub>3</sub>:C, Al<sub>2</sub>O<sub>3</sub>:C,Mg, and GAGG:Ce Crystals. [PDF]
Witkiewicz-Lukaszek S +4 more
europepmc +1 more source
Abstract Background and Purpose GABAA receptors (GABAARs) are heteropentameric ion channels that control almost all CNS functions, including spinal nociception. Most GABAARs contain a γ2 subunit but differ in their α and β subunit composition. TPA023B is an α2/α3 subtype selective, non‐sedative, positive allosteric modulator (PAM) with antihyperalgesic
Elena Neumann +12 more
wiley +1 more source
High magnification optical imaging systems for the characterization of soft X-ray focii. [PDF]
Al Haddad A +30 more
europepmc +1 more source
Background and Purpose Dopamine receptor agonists, particularly targeting the dopamine D2L receptor (D2LR), have been used to treat Parkinson's disease (PD). However, valvular heart disease and somnolence, mainly caused by activating the serotonin 5‐HT2B receptor (5‐HT2BR) and dopamine D3 receptor (D3R), respectively, currently challenge their clinical
Takayuki Suzuki +4 more
wiley +1 more source

