Results 241 to 250 of about 51,769 (308)

An LC–MS/MS Method for the Quantitation of Metabolites M9, M12, and M20 of Bexicaserin in Human Cerebrospinal Fluid

open access: yesBiomedical Chromatography, Volume 40, Issue 2, February 2026.
ABSTRACT The investigational molecule bexicaserin is a highly selective 5‐HT2C superagonist currently in Phase 3 clinical studies for the treatment of seizures associated with developmental and epileptic encephalopathies (DEEs). To facilitate its clinical development, a simple LC–MS/MS method was developed and validated for the quantitative estimation ...
Raja Reddy Kallem   +5 more
wiley   +1 more source

Astrocyte MCT1 Expression Does Not Contribute to the Axonal Degenerative Phenotype Observed With Ubiquitous MCT1 Depletion

open access: yesGlia, Volume 74, Issue 2, February 2026.
Loss of astrocytic MCT1 does not cause late onset neurodegeneration. As ubiquitous MCT1 deletion causes axonal degeneration, oligodendrocytes and potentially other cells are more prominent drivers of MCT1‐mediated metabolic support of neurons. ABSTRACT We recently reported that the loss of oligodendrocyte metabolic support through the lactate and ...
Thomas Philips   +9 more
wiley   +1 more source

Development and characterization of phantoms to investigate the Flash effect with <i>Drosophila melanogaster</i> at an ultra-high dose rate radiotherapy linac. [PDF]

open access: yesPhys Imaging Radiat Oncol
Dal Bello R   +10 more
europepmc   +1 more source

Heterostructure Nanoscintillator for Matching Radiation Absorbing Layers with Fast Light-Emitting Layers. [PDF]

open access: yesNano Lett
Be'er O   +8 more
europepmc   +1 more source

Crystal growth and characterization of 1-inch GTAGG: Ce single crystal for sub-micron resolution synchrotron radiation X-ray imaging. [PDF]

open access: yesSci Rep
Omuro K   +17 more
europepmc   +1 more source

A lung tumor-on-a-chip model recapitulates the effect of hypoxia on radiotherapy response and FDG-PET imaging. [PDF]

open access: yesLab Chip
Nasiri R   +8 more
europepmc   +1 more source

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