Results 141 to 150 of about 3,271 (204)

P-1341. Monotherapy with Trimethroprim/Sulfamethoxazole or Minocycline for the Treatment of Stenotrophomonas maltophilia Infections

Open Forum Infectious Diseases
Background Trimethoprim/sulfamethoxazole (TMP/SMX) and minocycline (MINO) are both recommended for the treatment of Stenotrophomonas maltophilia, however, there is a lack of comparative clinical data and IDSA guidance recommends against the use of ...
Zakery Kujat, Amima Mahmood, Alex S Huang, Shannon Olson, Paige Roberts, Jing J. Zhao, Marco R. Scipione   +6 more
semanticscholar   +1 more source

P-755. Comparison of Clinical and Safety Outcomes with Adjunctive Linezolid Versus Clindamycin in the Treatment of Necrotizing Soft Tissue Infections

Open Forum Infectious Diseases
Background With decreasing susceptibility of Streptococcus pyogenes (GAS) to clindamycin, the Detroit Medical Center (DMC) has adopted linezolid as the toxin suppressive agent in the empiric treatment of necrotizing soft tissue infections (NSTIs).
Andrew Matlob, Jing J. Zhao, Marco R. Scipione, Alex S Huang, Shannon Olson   +4 more
semanticscholar   +1 more source

P-1210. Real-World Efficacy and Safety of Meropenem-Vaborbactam in Patients with Moderate to Severe Renal Impairment

Open Forum Infectious Diseases
Background Meropenem-vaborbactam (MEV) is a novel β-lactam β-lactamase inhibitor combination approved in the United States for the treatment of complicated urinary tract infections caused by resistant organisms. Its spectrum includes carbapenem-resistant
Sean R. Van Helden, Kaylee E. Caniff, Mohammed Al Musawa, S. Alosaimy, A. Lagnf, Chloe Judd, Marco R. Scipione, Jing J. Zhao, Taryn A. Eubank, Kevin W. Garey, W. Kufel, Tamara Krekel, Karen K. Tan, Elisabeth Chandler, Jacqueline A Aramburo, Dev Chatterji, Samantha D Walker, C. Yost, Jacqueline M Muscat, Justin A Andrade, John Cerenzio, K. Raja, Taylor Morrisette, Sarah C J Jorgensen, Ryan P Mynatt, Travis J Carlson, D. Allen, Kailynn J DeRonde, Ana Vega, Lilian M. Abbo, Venugopalan Veena, Vasilios Athans, S. Saw, K. Claeys, Matthew Miller, Kyle C. Molina, Lee Amaya, J. Ortwine, M. Veve, M. Rybak   +39 more
semanticscholar   +1 more source

Beyond traditional metrics: Assessing OpenAlex and Scopus for SSH research evaluation

Journal of information science
Recent debates on research evaluation in the Social Sciences and Humanities (SSH) have underscored the limitations of traditional bibliometric databases – such as Scopus and Web of Science – in capturing the linguistic and regional diversity ...
T. Cicero, S. Sarlo
semanticscholar   +1 more source

P-70. A Comparison of Clinical and Safety Outcomes for Patients with Vancomycin Resistant Enterococcus Faecium Bacteremia Treated with High Dose Daptomycin Based on Isolate MIC

Open Forum Infectious Diseases
Background Daptomycin (DAP) is a frequently utilized treatment option for patients with vancomycin-resistant Enterococci (VRE) bacteremia. Prior study data has shown poorer clinical outcomes for patients with VRE bacteremia and isolate MICs of >1µg/mL ...
Taylor Wisdom, Marco R. Scipione
semanticscholar   +1 more source

Exploring structure–activity relationships of pyrrolyl diketo acid derivatives as non-nucleoside inhibitors of terminal deoxynucleotidyl transferase enzyme

Journal of Enzyme Inhibition and Medicinal Chemistry
Terminal deoxynucleotidyl transferase (TdT) is overexpressed in some cancer types, where it drives the mutagenic repair of double strand breaks through non canonical non-homologous end joining pathway.
V. N. Madia, Nadia Garibaldi, Davide Ialongo, E. Patacchini, Valeria Tudino, Giuseppe Ruggieri, Laura Zarbo, Emanuele Cara, Antonio Coluccia, M. Artico, L. Scipione, A. Messore, Francesco Saccoliti, Elisa Mentegari, Giovanni Maga, R. Di Santo, E. Crespan, R. Costi   +17 more
semanticscholar   +1 more source

Early Clinical Response is Associated With a Decreased Risk of Recurrent Pseudomonas aeruginosa Ventilator-Associated Pneumonia

The Annals of Pharmacotherapy
Background: Current data suggest that short-course therapy for Pseudomonas aeruginosa ventilator-associated pneumonia (PA-VAP) may increase the risk of recurrent pneumonia.
Alex S Huang, Jing J. Zhao, Ryan Gumbleton, Marco R. Scipione   +3 more
semanticscholar   +1 more source

N-alkyl and N-benzyl indoles are anti-SARS-CoV-2 agents and nsp13 inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry
COVID-19 pandemic stimulated tremendous efforts to develop therapeutic strategies targeting SARS-CoV-2, leading to the evaluation of a wide range of potential treatments in clinical trials.
Aurora Albano, Roberta Emmolo, Riccardo De Santis, E. Patacchini, V. N. Madia, Stefania Maloccu, Davide Ialongo, Giuseppe Ruggieri, M. Arpacioglu, L. Scipione, Francesco Saccoliti, Donatella Amatore, G. Grilli, F. Lista, Francesca Esposito, E. Tramontano, A. Corona, R. Di Santo, R. Costi   +18 more
semanticscholar   +1 more source

Scipione Ammirato Della Segretezza... / Scipione Ammirato...

2011
Marca tip. en port.
openaire   +1 more source

Memoria by Multiplication: The Cornelii Scipiones in Monumental Memory

Omnium Annalium Monumenta: Historical Writing and Historical Evidence in Republican Rome, 2018
Karl-Joachim Hölkeskamp
semanticscholar   +1 more source