Results 61 to 70 of about 2,197,634 (177)

OCT applications in contact lens fitting

, 2022
Optical Coherence Tomography (OCT) is a noninvasive, high-speed, high-resolution imaging technology based in the Michaelson interferometry. A near-infrared light beam is used to register the intensity variations for the light backscattered on each sample
Cerviño, Alejandro, Serramito Blanco, María, Carracedo Rodríguez, Juan Gonzalo, Romaguera Planells, María, Valdés Soria, Gonzalo   +4 more
core   +1 more source

From Molecular Targets to Advanced Delivery Systems: Aptamers for Precision Ocular Therapeutics

Advanced Therapeutics, Volume 9, Issue 10, October 2026.
Aptamer‐based strategies are revolutionizing ocular disease management through highly specific molecular recognition of disease specific molecular targets. This review systematically integrates therapeutic aptamer sequences, diagnostic aptasensor platforms, and targeted delivery strategies, highlighting design principles, ocular bioavailability ...
Minal Thacker, Ka‐Ying Wong, Liping Zhou, Man‐Sau Wong, Juewen Liu   +4 more
wiley   +1 more source

Corneal tissue properties following scleral lens wear using Scheimpflug imaging

, 2020
Purpose: To investigate the effect of short-term scleral lens wear on the corneal stroma at a macroscopic (thickness) and microscopic (within tissue) level, including regional variations.
Consejo, A, Maciej Wojtkowski, Alonso-Caneiro, D, Wojtkowski, M, Stephen J Vincent, Alejandra Consejo, David Alonso‐Caneiro, Vincent, SJ   +7 more
core   +1 more source

Mesenchymal Stem Cell‐Derived Extracellular Vesicles Ameliorate NaIO3‐Induced Dry AMD by Delivering miR‐486‐3p to Inhibit Lipocalin‐2‐Mediated Ferroptosis

MedComm, Volume 7, Issue 10, October 2026.
Our study reveals a novel mechanism by which MSC‐derived EVs alleviate NaIO3‐induced dry AMD‐like pathology. MSC‐EVs deliver miR‐486‐3p into retinal cells to directly inhibit the ferroptosis‐promoting target gene Lcn2. Concurrently, downregulated Lcn2 restores intracellular Gpx4 expression, thereby suppressing ferroptosis and rescuing retinal ...
Zheng Li, Tujing Zhao, Lin Ye, Runze Li, Huaping Tian, Ruilin Liao, Lulin Huang   +6 more
wiley   +1 more source

Contact Lens Visual Rehabilitation in Keratoconus and Corneal Keratoplasty

Journal of Ophthalmology, 2012
Keratoconus is the most common corneal distrophy. It’s a noninflammatory progressive thinning process that leads to conical ectasia of the cornea, causing high myopia and astigmatism.
Yelda Ozkurt, Mehmet Atakan, Tugba Gencaga, Sezen Akkaya   +3 more
doaj   +1 more source

Understanding higher‐order aberrations in keratoconus

Optometry and Vision Science, Volume 103, Issue 10, October 2026.
ABSTRACT Keratoconus is characterized by progressive thinning and increasing irregularity of the cornea, leading to substantial degradation in optical quality through the induction of both lower‐ and higher‐order aberrations (HOAs). In addition to inducing myopic and astigmatic refractive error, asymmetric corneal steepening generates complex optical ...
Gavin Swartz, Khyber Alam, Alex Gentle, Laura E. Downie   +3 more
wiley   +1 more source

Ocular Surface Temperature During Scleral Lens Wearing in Patients With Keratoconus

, 2016
Accepted March 28, 2016 ; post-author corrections May 19, 2016.Objective: To evaluate the ocular surface temperature using an infrared thermography camera before and after wearing scleral lens in patients with keratoconus and correlate these results with
Wang, Zicheng, Carballo Álvarez, Jesús, Martín Gil, Alba, Carracedo Rodríguez, Juan Gonzalo, Serramito Blanco, María, Pintor, Jesús   +5 more
core   +1 more source

A Whole‐Head Finite Element Model for Electrical Neuromodulation via Visual Brain‐Machine Interfaces

Advanced Science, Volume 13, Issue 52, 18 September 2026.
A multimodal, personalized head model is presented that integrates the entire visual pathway with surrounding tissues to simulate electrical stimulation of the optic nerve. In vivo validation in humans and goats, plus systematic component‐elimination analysis, demonstrates the high accuracy of the comprehensive model.
Shengjian Lu, Tonghe Yang, Yuan Geng, Huan Wu, Yangrui Huang, Te Zheng, Haodi Chen, Shurui Huang, Yi Cao, Jian Yang, Wentao Yan, Yikui Zhang, Wencan Wu   +12 more
wiley   +1 more source

Posterior cornea and thickness changes after scleral lens wear in keratoconus patients [PDF]

, 2019
Purpose: To evaluate the changes in the corneal thickness, anterior chamber depth and posterior corneal curvature and aberrations after scleral lens wear in keratoconus patients with and without intrastromal corneal ring segments (ICRS).
Carballo, Jesús, Carracedo Rodríguez, Juan Gonzalo, Piñero, David P., Jesús Carballo, David Piñero, Michael Lipson, Carracedo, Gonzalo, Carlos Carpena-Torres, Maria Serramito, Carballo Álvarez, Jesús, Gonzalo Carracedo, Serramito Blanco, María, Carpena Torres, Carlos, Piñero, David Pablo, Serramito, Maria, Lipson, Michael, Carpena-Torres, Carlos   +16 more
core   +1 more source

Neurotrophic Signaling, Sleep Physiology, and Retinal Neuroprotection: Integrative Mechanisms and Therapeutic Implications for Glaucoma

Sensory Neuroscience, Volume 2, Issue 3, September 2026.
Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa, Emiliano Terán, Javier A. Magaña‐Gómez, Loranda Calderón‐Zamora, Beatriz K. De la Herrán‐Arita, Alberto K. De la Herrán‐Arita   +5 more
wiley   +1 more source