Quantifying Graft Detachment after Descemet's Membrane Endothelial Keratoplasty with Deep Convolutional Neural Networks [PDF]
arXiv, 2020 Purpose: We developed a method to automatically locate and quantify graft detachment after Descemet's Membrane Endothelial Keratoplasty (DMEK) in Anterior Segment Optical Coherence Tomography (AS-OCT) scans. Methods: 1280 AS-OCT B-scans were annotated by a DMEK expert.
arxiv
Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate [PDF]
, 2014 Subretinal injection of sodium hyaluronate is a widely accepted method of inducing retinal detachment (RD)1-15. However, the height and duration of RD or the occurrence of subretinal hemorrhage can affect photoreceptor cell death in the detached retina16-
Matsumoto, Hidetaka +2 more
core +1 more source
Identification of primary angle-closure on AS-OCT images with Convolutional Neural Networks [PDF]
arXiv, 2019 Primary angle-closure disease (PACD) is a severe retinal disease, which might cause irreversible vision loss. In clinic, accurate identification of angle-closure and localization of the scleral spur's position on anterior segment optical coherence tomography (AS-OCT) is essential for the diagnosis of PACD.
arxiv
AI-based Clinical Assessment of Optic Nerve Head Robustness Superseding Biomechanical Testing [PDF]
arXiv, 2022 $\mathbf{Purpose}$: To use artificial intelligence (AI) to: (1) exploit biomechanical knowledge of the optic nerve head (ONH) from a relatively large population; (2) assess ONH robustness from a single optical coherence tomography (OCT) scan of the ONH; (3) identify what critical three-dimensional (3D) structural features make a given ONH robust ...
arxiv
Rapidly dissolving polymeric microneedles for minimally invasive intraocular drug delivery [PDF]
, 2016 In this study, dissolving microneedles (MNs) were used to enhance ocular drug delivery of macromolecules. MNs were fabricated using polyvinylpyrrolidone (PVP) polymer of various molecular weights (MWs) containing three model molecules of increasing MW ...
Ali, Ahlam +5 more
core +1 more source
Deep Learning Algorithms to Isolate and Quantify the Structures of the Anterior Segment in Optical Coherence Tomography Images [PDF]
arXiv, 2019 Accurate isolation and quantification of intraocular dimensions in the anterior segment (AS) of the eye using optical coherence tomography (OCT) images is important in the diagnosis and treatment of many eye diseases, especially angle closure glaucoma.
arxiv
Appraisal of patient-reported outcome measures in analogous diseases and recommendations for use in phase II and III clinical trials of pyruvate kinase deficiency [PDF]
, 2018 Purpose: Pyruvate kinase deficiency (PKD) is a rare disease and understanding of its epidemiology and associated burden remains limited. With no current curative therapy, clinical manifestations can be life threatening, clinically managed by maintaining ...
Ionova, Tatyana +3 more
core +1 more source
Estudo comparativo entre as manifestações oftalmológicas, sorológicas e resposta terapêutica de pacientes com esclerite isolada e esclerite associada a doenças sistêmicas [PDF]
, 2011 INTRODUCTION: Scleritis is a rare, progressive and serious disease, the signs of which are inflammation and edema of episcleral and scleral tissues and is greatly associated with systemic rheumatoid diseases.
Freitas, Denise de +5 more
core +2 more sources
Effects of age and diabetes on scleral stiffness.
Journal of Biomechanical Engineering, 2015 The effects of diabetes on the collagen structure and material properties of the sclera are unknown but may be important to elucidate whether diabetes is a risk factor for major ocular diseases such as glaucoma.
Baptiste Coudrillier +6 more
semanticscholar +1 more source
Retinal Detachment Surgery at Nepal Eye Hospital
Journal of Nepal Medical Association, 2009 Introduction:Retinal diseases are one of the important causes of blindness in Nepal. This study is done with objectives of fi nding the outcome of retinal detachment surgery.
O K Malla +4 more
doaj +1 more source