Results 141 to 150 of about 25,913 (280)

Progression and topographic subtypes of Terrien marginal degeneration

Acta Ophthalmologica, Volume 104, Issue 1, Page 33-43, February 2026.
Abstract Purpose To report long‐term outcomes and to search for immunological and genetic risk factors in Terrien marginal degeneration (TMD). Methods Retrospective, in part prospective, hospital‐based longitudinal follow‐up study of 32 eyes of 16 Finnish patients from 2012 to 2023. Median follow‐up was 7.3 years (range, 0.3–15.2).
Minna Ruutila, Pauliina Repo, Annamari T. Immonen, Joni A. Turunen, Marja‐Liisa Lokki, A. Inkeri Lokki, Jukka Moilanen, Kari Krootila, Tero T. Kivelä   +8 more
wiley   +1 more source

Full Thickness Prophylactic Scleral Windows Decrease the Rate of Choroidal Effusion and Drainage Surgery after Ahmed Glaucoma Valve Implantation

Journal of Ophthalmic & Vision Research
Purpose: To evaluate the effect of creating a full-thickness prophylactic scleral window (PSW) during Ahmed glaucoma valve (AGV) surgery on the rate of postoperative choroidal effusion and choroidal drainage surgery.
Afsoon Baghbanmanesh, Masoumeh Sadat Masoumpour, Reza Razeghinejad   +2 more
doaj   +1 more source

Impact of anti‐VEGF therapy versus laser therapy on mortality and treatment outcomes in retinopathy of prematurity: A systematic review and meta‐analysis

Acta Ophthalmologica, Volume 104, Issue 1, Page e1-e17, February 2026.
Abstract Purpose Retinopathy of prematurity (ROP) is a major cause of childhood blindness, and selecting the optimal treatment between anti‐vascular endothelial growth factor (anti‐VEGF) and laser therapy is crucial. Understanding their impact on key outcomes, particularly mortality, is essential for informed clinical decision‐making.
Wei‐De Wang, Ya‐Hsin Yao, Chiao‐Hsin Lan, Shih‐Heng Hung, Ta‐Hsin Tsung, Yann‐Guang Chen, Da‐Wen Lu, Jiann‐Torng Chen, Ke‐Hung Chien, Shu‐I Pao, Wei‐Ting Yen   +10 more
wiley   +1 more source

Process and Outcomes of Fitting Corneoscleral Profilometry-Driven Scleral Lenses for Patients With Ocular Surface Disease [PDF]

Hannah Yoon, Jennifer Harthan, William Skoog, Jennifer Swingle Fogt, Amy Nau, Cherie B. Nau, Muriel Schornack, Ellen Shorter   +7 more
openalex   +1 more source

Muscle tendon elongation with bovine pericardium (Tutopatch®) in patients with Graves’ orbitopathy; a prospective, observational, multicentre study

Acta Ophthalmologica, Volume 104, Issue 1, Page e18-e27, February 2026.
Abstract Purpose Patients with severe ocular motility restriction and/or large angle strabismus due to Graves' orbitopathy (GO) cannot be adequately addressed with conventional strabismus surgery using large muscle recessions. Muscle tendon elongation surgery, using a spacer of bovine pericardium (Tutopatch®) has emerged as a valuable alternative.
H. M. Jellema, M. Oeverhaus, A. Eckstein, I. Mombaerts, R. J. H. M. Kloos, D. T. Hartong, P. Nieuwkerk, P. Saeed   +7 more
wiley   +1 more source

Effect of axial elongation on anterior scleral thickness in myopia

Indian Journal of Ophthalmology
Objective: This study aimed to investigate the effect of axial elongation on anterior scleral thickness (AST) in myopia. Methods: The convenience sampling method was used to select 122 patients without ocular or systemic diseases affecting ametropia in ...
Hui Yan, Jie Li, Cheng Wang, Cai-Qiu Mei
doaj   +1 more source

Prevalence of Ocular Surface Disease and Corneal Irregularity and Outcomes in Patients Using Therapeutic Scleral Lenses at a Tertiary Care Center

, 2019
Angelica C. Scanzera, Sneha Bontu, Charlotte E. Joslin, T. McMahon, Mark I. Rosenblatt, Ellen Shorter   +5 more
openalex   +2 more sources

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk, JoAnn C. L. Schuh, Brad Bolon, Valerie S. Thomas, Jeffrey I. Everitt, Abraham Nyska, Jaime Paulin   +6 more
wiley   +1 more source

Advancements in materials and fabrication techniques for microneedle ocular patch: a comprehensive review

Discover Applied Sciences
With the increasing prevalence of ocular diseases, there is an urgent need to look beyond conventional formulations, such as eye drops, ointments, and intravitreal injections, to treat various ocular diseases.
Karishma Sharma, Aiswarya Ramachandran, Venkata Vamsi Krishna Venuganti, Vishal Raval   +3 more
doaj   +1 more source

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen, Min Zhu, Xingyan Fan, Kangjia Lv, Kuan Jiang, Yuchen Zhang, Haoliang Zhang, Xinming Qi, Benjamin TK Lee, Yakun Wan, Gang Wei, Kun Liu, Xun Xu   +12 more
wiley   +1 more source