Results 61 to 70 of about 9,110,669 (238)

Drug Delivery Technologies for the Treatment of Age‐Related Macular Degeneration

Advanced Science, EarlyView.
There are multiple therapeutic agents available for the treatment of both dry age‐related macular degeneration (AMD) and wet AMD. It is essential to continue innovation by introducing new drug delivery technologies that can incorporate those along with patient compliance and the accessibility of the technology into the early stages of research and ...
J Jesus Rodriguez‐Cruz, Jessica Cutrufello, Michael Lam, Shreya Nallaparaju, Nicholas A. Peppas   +4 more
wiley   +1 more source

Establishment of a novel alloxan‐induced rabbit model exhibiting unique diabetic retinal neuropathy features assessed via ERG + VEP

Animal Models and Experimental Medicine, EarlyView.
Study workflow. Neuroretinal changes were observed in alloxan‐induced diabetic rabbits, while the retinal vasculature remained unaffected, indicating the successful establishment of a diabetic neuroretinal model. Abstract Background Diabetic retinal neuropathy (DRN) leads to significant visual impairment; however, no existing animal model fully ...
Xinlu Li, Xiaojing Dong, Defei Feng, Han Hu, Bai Li, Zhongjian Liu, Wei He, Chenchen Huang, Zhizhou Shi, Yan Mei   +9 more
wiley   +1 more source

Applications of Mitomycin C in Cornea and External Disease

Türk Oftalmoloji Dergisi, 2023
Isolated from Streptomyces caespitosus, mitomycin C (MMC) has various applications in the management of corneal and external disease due to its ability to modulate cellular proliferation.
Marcos A. Crespo, Christopher J. Rapuano, Zeba A. Syed   +2 more
doaj   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Microsaccades Tracking by Secondary Speckle Pattern Analysis

Journal of Biophotonics, EarlyView.
A new approach for detecting microsaccades is introduced using secondary speckle patterns reflected from the sclera. This method offers potential benefits in capturing subtle eye movements and overcoming limitations in traditional pupil‐tracking systems.
Ola Shteinberg, Sergey Agdarov, Yafim Beiderman, Yoram S. Bonneh, Inbal Ziv, Zeev Kalyuzhner, Zeev Zalevsky   +6 more
wiley   +1 more source

An Evidence-Based Narrative Review of Scleral Hypoxia Theory in Myopia: From Mechanisms to Treatments

International Journal of Molecular Sciences
Myopia is one of the dominant causes of visual impairment in the world. Pathological myopia could even lead to other serious eye diseases. Researchers have reached a consensus that myopia could be caused by both environmental and genetic risk factors ...
Qin Xiao, Xiang Zhang, Zhangling Chen, Yunjun Zou, Chang-Fa Tang   +4 more
semanticscholar   +1 more source

Rectal budesonide: A potential game changer after Kasai hepatoportoenterostomy

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Intravenous or oral steroid administration in patients with biliary atresia (BA) after Kasai hepatoportoenterostomy (HPE) is commonly practiced, however, the benefits remain controversial. Some studies suggest no positive effects while risking steroid associated side effects.
Stefanie Langreen, Nathalie Pauer, Eva D. Pfister, Norman Junge, Ulrich Baumann, Omid Madadi‐Sanjani, Claus Petersen, Jens Dingemann, Nagoud Schukfeh   +8 more
wiley   +1 more source

Prevalence and factors associated with scleral hyaline plaque: clinical study of older adults in southeastern Brazil

Clinical Ophthalmology, 2015
Soraya Horowitz,1 Nadyr Damasceno,1 Eduardo Damasceno21Department of Ophthalmology, Hospital Naval Marcilio Dias, Rio de Janeiro, 2Department of Ophthalmology, Universidade Federal Fluminense, Niterói, BrazilPurpose: To investigate ...
Horowitz S, Damasceno N, Damasceno E
doaj  

Drug‐induced liver injury associated with selective androgen receptor modulators in an adolescent patient

JPGN Reports, EarlyView.
ABSTRACT Selective androgenic receptor modulators (SARMs) have similar properties to anabolic steroids but bind to androgen receptors in a tissue‐specific manner. Studies have investigated the benefits of SARMs in promoting bone and muscle growth while limiting the adverse effects of androgenic stimulation of other organs.
David J. Katibian, Laura E. Bauman, Katayoon Shayan, D. Brent Polk   +3 more
wiley   +1 more source

What is the Real Cause of Glaucoma? [PDF]

Iranian Journal of Medical Physics, 2010
Introduction: The term glaucoma refers to a group of diseases that have a characteristic optic neuropathy with associated visual field loss in common. Intraocular pressure has been considered to be the only causal factor for glaucoma and the only factor ...
Alireza Mehdizadeh, Amin Hosseinzadeh
doaj   +1 more source