Results 201 to 210 of about 1,415,478 (254)
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Cross‐sectional quantitative validation of the paediatric Localized Scleroderma Quality of Life Instrument (LoSQI): A disease‐specific patient‐reported outcome measure

Journal of the European Academy of Dermatology and Venereology, 2023
The Localized Scleroderma Quality of Life Instrument (LoSQI) is a disease‐specific patient‐reported outcome (PRO) measure designed for children and adolescents with localized scleroderma (LS; morphea).
C. Zigler   +10 more
semanticscholar   +1 more source

Adipose-Derived Stem Cells Attenuate Skin Fibrosis and Improve Fat Retention of a Localized Scleroderma Mouse Model

Plastic and Reconstructive Surgery, 2022
Background: Although autologous fat grafting is a feasible surgical technique to improve facial deformity in patients with localized scleroderma, its success is limited by the low graft retention induced by the local inflammatory environment.
H. C. Wang   +7 more
semanticscholar   +1 more source

Identification of lncRNA expression profiles in pediatric localized scleroderma

Journal of Cosmetic Dermatology, 2022
The role and potential molecular mechanism of inflammatory cells in pediatric localized scleroderma are poorly investigated. In this study, we first investigated the profiling of inflammatory cells in skin samples from pediatric localized scleroderma ...
Yi-nv Gong   +3 more
semanticscholar   +1 more source

Aesthetic and therapeutic outcome of fat grafting for localized Scleroderma treatment: From basic study to clinical application

Journal of Cosmetic Dermatology, 2021
Localized scleroderma (LoS) is a rare autoimmune disease characterized by skin fibrosis and subcutaneous tissue atrophy, resulting in aesthetic impairment on patients.
H. C. Wang   +3 more
semanticscholar   +1 more source

Extracutaneous Involvement Is Common and Associated with Prolonged Disease Activity and Greater Impact in Juvenile Localized Scleroderma.

Rheumatology, 2021
OBJECTIVE To evaluate factors associated with extracutaneous involvement (ECI) in juvenile localized scleroderma (jLS). METHODS A prospective, multi-center, 6-month observational study was performed.
Suzanne C. Li   +10 more
semanticscholar   +1 more source

Localized scleroderma: actual insights and new biomarkers

International Journal of Dermatology, 2021
Localized scleroderma (LS, morphea, limited scleroderma, focal scleroderma) is a chronic autoimmune disease characterized by a progressive damage to the connective tissue with a predominance of fibrosclerotic disorders in the skin and the subcutaneous ...
E. Snarskaya, K. Vasileva
semanticscholar   +1 more source

Transcriptomic Evaluation of Juvenile Localized Scleroderma Skin With Histologic and Clinical Correlation

Arthritis & Rheumatology, 2021
Juvenile localized scleroderma (LS) is an autoimmune disease of the skin whose pathogenesis is not well understood due to the rarity of the disease. This study was undertaken to determine the skin transcriptome in skin biopsy tissue from children with ...
Christina Schutt   +8 more
semanticscholar   +1 more source

Localized scleroderma of the breast [PDF]

open access: possibleEuropean Radiology, 2001
We report a 44-year-old patient with right-breast morphea. Mammography, MRI and needle biopsy were used for assessment of the case. Mammography demonstrated thickening of the skin and the subcutaneous tissue. The MRI showed replacement of the subcutaneous and breast fat by a low signal intensity, non-enhancing tissue.
Teresa Ibáñez   +3 more
openaire   +2 more sources

The Risk of Conducting Overgrafting of Fat for Treating Facial Atrophy Induced by Localized Scleroderma

Facial Plastic Surgery, 2021
Localized scleroderma is a rare autoimmune connective tissue disorder leading to serious long-term aesthetic impairment in patients who need surgical treatment to gain facial improvement.
H. C. Wang, Xiaojun Wang
semanticscholar   +1 more source

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