Results 91 to 100 of about 84,856 (259)

Atezolizumab-induced Sclerosing Cholangitis in a patient with lung cancer: A case report

open access: yesCancer Treatment and Research Communications, 2021
Atezolizumab is an immune checkpoint inhibitor that is a key drug in non-small-cell lung cancer treatment. However, it can cause immune-related adverse events, including liver injury.
Shinji Nabeshima   +8 more
doaj  

Multiple therapeutic targets in rare cholestatic liver diseases: Time to redefine treatment strategies

open access: yesAnnals of Hepatology, 2020
Primary biliary cholangitis and primary sclerosing cholangitis are rare diseases affecting the bile ducts and the liver. The limited knowledge of their pathogenesis leads to limited therapeutic options.
Alessio Gerussi   +5 more
doaj  

IgG4-associated sclerosing cholangitis: a diagnosis that may change the course of events (review of the literature and a clinical case)

open access: yesAlʹmanah Kliničeskoj Mediciny, 2018
Immunoglobulin G4-associated sclerosing cholangitis (IgG4-SC) can mimic primary sclerosing cholangitis, cholangiocarcinoma, and pancreatic adenocarcinoma. Its proper diagnosis allows for an adequate therapy and an improvement of the outcomes. The article
E. V. Vinnitskaya   +4 more
doaj   +1 more source

Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis.

open access: yesGastroenterology, 2017
BACKGROUND & AIMS Primary sclerosing cholangitis (PSC) is an orphan hepatobiliary disorder associated with inflammatory bowel disease (IBD). We aimed to estimate the risk of disease progression based on distinct clinical phenotypes in a large ...
T. Weismüller   +58 more
semanticscholar   +1 more source

Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis.

open access: yesJournal of Hepatology, 2021
M. Reich   +32 more
semanticscholar   +1 more source

Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis

open access: yesWorld Journal of Gastroenterology, 2017
AIM To characterize the gut bacterial microbiota of patients with primary sclerosing cholangitis (PSC) and ulcerative colitis (UC). METHODS Stool samples were collected and relevant clinical data obtained from 106 study participants, 43 PSC patients with
L. Bajer   +9 more
semanticscholar   +1 more source

Ursodeoxycholic acid for treatment of primary sclerosing cholangitis: A placebo-controlled trial [PDF]

open access: bronze, 1992
Ulrich Beuers   +9 more
openalex   +1 more source

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