Results 181 to 190 of about 106,721 (360)

Dye-based chromoendoscopy detects more neoplasia than white light endoscopy in patients with primary sclerosing cholangitis and IBD

Endoscopy International Open
Background and study aims Patients with primary sclerosing cholangitis and inflammatory bowel disease (IBD) have a high risk of colorectal cancer.
Rodrigo V Motta, Vipin Gupta, Karen Hartery, Paul Bassett, Simon J Leedham, Roger W Chapman, Simon PL Travis, Emma L Culver, James E. East   +8 more
doaj   +1 more source

Non‐Response to Obeticholic Acid Is Associated With Heightened Risks of Developing Clinical Events in Primary Biliary Cholangitis

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 4, Page 494-506, February 2026.
In a multi‐centre study of obeticholic acid in primary biliary cholangitis, 45% discontinued the drug over 4 years, with 11% moving to combination therapy (fibrates). Of those continuing, response rates increased from 37% (1 year) to 55% (4 years). Non‐response at 12 months and cirrhosis were independent predictors of liver‐related events.
Nadir Abbas, Rachel Smith, Ellina Lytvyak, Miki Scaravaglio, Neil Halliday, Amal Almahroos, Nadia Eden, Diane Lloyd‐Madden, Sanchit Sharma, James Ferguson, Jessica K. Dyson, Douglas Thorburn, David Jones, Aldo J. Montano‐Loza, Marco Carbone, Pietro Invernizzi, George Mells, Emma L. Culver, Palak J. Trivedi   +18 more
wiley   +1 more source

Intrahepatic bile duct strictures in a liver allograft recipient mimicking recurrent primary sclerosing cholangitis - Follow-up of a case report [PDF]

, 1991
Demetris, AJ, Gordon, R, Hartman, GG, Lerut, J, Starzl, TE   +4 more
core   +1 more source

Soluble CD163 as a Biomarker of Liver Fibrosis and Inflammation in Liver Transplant Recipients

Clinical Transplantation, Volume 40, Issue 2, February 2026.
ABSTRACT Background and Aims Post liver transplantation (LT) inflammation and fibrosis are clinical challenges that may affect long‐term outcomes. We aimed to investigate sCD163 as a biomarker of liver fibrosis in LT recipients and compare it with the Fibrosis 4 (FIB‐4) score and FibroScan.
Emilie Høegholm Ernst Lauridsen, Rasmus Hvidbjerg Gantzel, Moises Alberto Suarez‐Zdunek, Mette Bak Nielsen, Allan Rasmussen, Susanne Dam Nielsen, Henning Grønbæk, Gerda Elisabeth Villadsen   +7 more
wiley   +1 more source

164 A Historical Cohort Study Comparing the Clinical Outcome of Ulcerative Colitis and Crohn's Disease in the Presence of Primary Sclerosing Cholangitis

, 2012
Udayakumar Navaneethan, Preethi G.K. Venkatesh, Bret A. Lashner, Feza H. Remzi, Pokala R. Kiran, Bo Shen, John J. Fung   +6 more
openalex   +1 more source

A107 DISEASE DISTRIBUTION AND CLINICAL FEATURES OF INFLAMMATORY BOWEL DISEASE IN PATIENTS WITH PRIMARY SCLEROSING CHOLANGITIS: A SINGLE-CENTRE RETROSPECTIVE ANALYSIS [PDF]

, 2019
K Donaldson, Robert Enns, Brian Bressler, Hin Hin Ko   +3 more
openalex   +1 more source

A protective effect of inflammatory bowel disease on the severity of sclerosing cholangitis

Frontiers in Immunology
BackgroundPrimary sclerosing cholangitis (PSC) is a chronic liver disease marked by inflammation of the bile ducts and results in the development of strictures and fibrosis. A robust clinical correlation exists between PSC and inflammatory bowel disease (
Friederike Stumme, Friederike Stumme, Niklas Steffens, Babett Steglich, Babett Steglich, Babett Steglich, Franziska Mathies, Mikolaj Nawrocki, Mikolaj Nawrocki, Morsal Sabihi, Morsal Sabihi, Shiwa Soukou-Wargalla, Emilia Göke, Emilia Göke, Jan Kempski, Jan Kempski, Thorben Fründt, Sören Weidemann, Christoph Schramm, Christoph Schramm, Christoph Schramm, Nicola Gagliani, Nicola Gagliani, Nicola Gagliani, Samuel Huber, Samuel Huber, Tanja Bedke, Tanja Bedke   +27 more
doaj   +1 more source

Unveiling the Burden of Steatotic Liver Disease: Mortality Risks by Subtype and Fibrosis Stage in a Nationwide Cohort

Liver International, Volume 46, Issue 2, February 2026.
ABSTRACT Background and Aims We investigated the associations between SLD, fibrosis stage, and all‐cause and cause‐specific mortality, with a focus on SLD subtypes. Methods We analysed 486 156 UK Biobank participants. SLD cases were identified using fatty liver index ≥ 60. Causes of death were confirmed via death registries.
Qi Feng, Pinelopi Manousou, Chioma N. Izzi‐Engbeaya, Rohit Loomba, Mark Thursz, Mark Woodward   +5 more
wiley   +1 more source

Mo1795 Mucosal IgG4 Cell Infiltration in Ulcerative Colitis (UC) is Linked to Disease Activity and Primary Sclerosing Cholangitis(PSC)

, 2012
Amit Raina, Dhiraj Yadav, Miguel Regueiro, Alyssa M. Krasinskas, Melissa Saul, Dee Ann M. Sapienza, David G. Binion, Douglas J. Hartman   +7 more
openalex   +1 more source

Challenges in Diagnosing Intrahepatic Cholangiolithiasis in a 39-Year-Old Patient

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to highlight the challenges of diagnosing and treating a patient with severe intrahepatic cholangiolithiasis.Key points. Primary sclerosing cholangitis is a chronic progressive liver disease characterized by destructive inflammation and fibrosis in ...
A. K. Guseva, O. N. Sergeyeva, T. P. Nekrasova, O. T. Imaraliev, A. V. Okhlobystin, Y. N. Shirokova, A. S. Ostrovskaya, M. S. Zharkova, A. S. Cherenda, V. T. Ivashkin   +9 more
doaj   +1 more source