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Sclerosing cholangitis in children
The Journal of Pediatrics, 1994We report on 56 children with sclerosing cholangitis (SC) seen between 1972 and 1992. The first symptoms occurred at a mean age of 3.7 years; 15 infants had neonatal cholestatic jaundice. At diagnosis, cholestatic jaundice was present in 25 children, hepatomegaly in 54, splenomegaly in 41, and ascites in 12.
Michelle Hadchouel+4 more
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The microbiota and the gut–liver axis in primary sclerosing cholangitis
Nature reviews: Gastroenterology & hepatology, 2022J. Hov, T. Karlsen
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Primary Sclerosing Cholangitis
Endoscopy, 1985Primary sclerosing cholangitis was diagnosed in 6 patients (4 men and 2 women), with ages ranging from 33 to 71 years. Four of them had ulcerative colitis, with an evolution from 8 to 21 years, the other two had Crohn's disease with 2 and 3 years of evolution.
A D Jorge, C Esley
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Hepatology Research, 2019
Autoimmune liver diseases (AILD) including autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC) impose a significant burden on public health, and it is important to estimate their prevalence.
A. Tanaka+5 more
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Autoimmune liver diseases (AILD) including autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC) impose a significant burden on public health, and it is important to estimate their prevalence.
A. Tanaka+5 more
semanticscholar +1 more source
Primary Sclerosing Cholangitis
Inflammatory Bowel Diseases, 2005Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammation and fibrosis of the intra- and extrahepatic bile ducts. An estimated 80% of patients in North America and Europe have coexistent inflammatory bowel disease (IBD). The underlying pathophysiology of PSC remains poorly understood.
Keith D. Lindor, Jayant A. Talwalkar
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Primary sclerosing cholangitis
The American Journal of Surgery, 1987Primary sclerosing cholangitis was seen in only 7 of 6,494 biliary operations performed between 1948 and 1979. Fifteen more cases were seen in 1,467 biliary operations performed over a recent 5 year period. Surgery was directed primarily towards the differential diagnosis between cholangiocarcinoma and primary sclerosing cholangitis of the upper bile ...
Thomas Taylor White, Michael J. Hart
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Primary Sclerosing Cholangitis
2011Primary sclerosing cholangitis (PSC) is a chronic liver condition which may affect both intra and extrahepatic biliary tree. Etiology of PSC remains to be fully elucidated but genetic, autoimmune, inflammatory and possibly infective factors could all contribute to its development.
Piotr Milkiewicz, Ewa Wunsch
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Primary Sclerosing Cholangitis
Archives of Internal Medicine, 1982Recent investigations have clarified the clinical, radiologic, and pathologic features of primary sclerosing cholangitis, a chronic fibrosing disorder affecting the biliary tree. This progressive, cholestatic biliary disease is diagnosed when an elevated serum alkaline phosphatase level and stricturing and beading of bile ducts on cholangiography are ...
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