Results 21 to 30 of about 84,856 (259)
Fast and flexible inference for joint models of multivariate longitudinal and survival data using Integrated Nested Laplace Approximations [PDF]
, 2022 Modeling longitudinal and survival data jointly offers many advantages such as addressing measurement error and missing data in the longitudinal processes, understanding and quantifying the association between the longitudinal markers and the survival events and predicting the risk of events based on the longitudinal markers.
arxiv +1 more source
World Journal of Surgical Oncology, 2018 Background Diagnostic work-ups in transplanted immunosuppressed patients are a challenge as non-specific findings may be interpreted as transplant-related complications. If the disease in question is rare and slowly developing like pseudomyxoma peritonei
Ebbe Billmann Thorgersen +4 more
doaj +1 more source
Altered gut microbial metabolism of essential nutrients in primary sclerosing cholangitis.
Gastroenterology, 2020 BACKGROUND AND AIMS To influence host and disease phenotype, compositional microbiome changes, which have been demonstrated in patients with primary sclerosing cholangitis (PSC), must be accompanied by functional changes.
M. Kummen +21 more
semanticscholar +1 more source
Current Opinion in Gastroenterology, 1995 Primary sclerosing cholangitis is a chronic cholestatic liver disease of unknown etiology. Immunogenetic factors are considered important in its pathogenesis. The genetic susceptibility to primary sclerosing cholangitis is associated, in part, with the HLA HLA-DRB1, DQA1, DQB1 haplotype.
Martins, E, Chapman, R
openaire +6 more sources
Current Opinion in Gastroenterology, 2004 Primary sclerosing cholangitis is a chronic cholestatic liver disease characterized by strictures of the biliary tree. It is immune mediated, although the precise cause remains unknown. Recent reports have shown a higher prevalence and burden of disease than was previously suspected.The research into the etiopathogenesis, epidemiology, diagnosis of ...
MacFaul, G, Chapman, R
openaire +5 more sources
Individual dynamic prediction of clinical endpoint from large dimensional longitudinal biomarker history: a landmark approach [PDF]
, 2021 The individual data collected throughout patient follow-up constitute crucial information for assessing the risk of a clinical event, and eventually for adapting a therapeutic strategy. Joint models and landmark models have been proposed to compute individual dynamic predictions from repeated measures to one or two markers.
arxiv +1 more source
Programmed cell death-1 inhibitor-related sclerosing cholangitis: A systematic review
World Journal of Gastroenterology, 2020 BACKGROUND Programmed cell death-1 (PD-1) inhibitor has been indicated for many types of malignancies. However, these inhibitors also cause immune-related adverse events.
T. Onoyama +8 more
semanticscholar +1 more source
Medicine, 2021 Introduction: Immune checkpoint inhibitors (ICIs), particularly anti-PD-1 antibody, have dramatically changed cancer treatment; however, fatal immune-related adverse events (irAEs) can develop.
Y. Hirasawa +25 more
semanticscholar +1 more source
Current Opinion in Gastroenterology, 2007 Primary sclerosing cholangitis is a chronic cholestatic liver disease characterized by strictures of the biliary tree complicated by cirrhosis and cholangiocarcinoma. It is immune mediated, although the precise aetiology remains unknown.Research into etiopathogenesis and epidemiology, diagnosis of cholangiocarcinoma, associations with inflammatory ...
Maggs, JR, Chapman, R
openaire +3 more sources
Difficulties in Diagnosing Isolated IgG4-associated Sclerosing Cholangitis
Journal of Digestive Endoscopy, 2019 The most common causes of recurrent cholangitis are biliary stones and neoplasia. Primary types of sclerosing cholangitis such as IgG4-associated sclerosing cholangitis (IgG4-SC) and primary sclerosing cholangitis (PSC) are rare causes of recurrent ...
Gábor Zsóri +3 more
doaj +1 more source